Search Results
Overview
| Uniprot ID | H0VLP7 |
|---|---|
| Protein Name | Proteasome activator complex subunit 1 |
| Gene Name | PSME3 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 99 | GPTYKKRKLDECEEA |
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome
Protein Sequence
10
MEKWVLKKRK
20
YLQSGGLSAS
30
HYNFRVDSFR
40
ERITSEAEDL
50
VANFFPKKLL
60
ELDSFLKEPI
70
LNIHDLTQIH
80
SDMNLPVPDP
90
ILLTNSHDGL
100
DGPTYKKRKL
110
DECEEALQGT
120
KVFVMPNGML
130
KSNQQLVDII
140
EKVKPEIRLL
150
IEKCNTVKMW
160
VQLLIPRIED
170
GNNFGVSIQE
180
ETVAELRTVE
190
SEAASYLDQI
200
SRYYITRAKL
VSK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0008537 | proteasome activator complex |
| Molecular Function | GO:0061133 | endopeptidase activator activity |
| Biological Process | GO:0019884 | antigen processing and presentation of exogenous antigen |
| Biological Process | GO:2000045 | regulation of G1/S transition of mitotic cell cycle |
| Biological Process | GO:0061136 | regulation of proteasomal protein catabolic process |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.