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Overview

Uniprot IDH0VM25
Protein NameAldo-keto reductase family 1 member A1
Gene NameAKR1A1
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
127 RGDNPFPKNADGTVR

Function

No function data available.

Protein Sequence

10 MAASCVLLHT 20 GQKMPLIGLG 30 TWKSEPGQVK 40 AAITYALSVG 50 YRHIDCAAVY 60 GNETEIGEAL 70 KANVGPGKAV 80 PREEVFVTSK 90 LWNTKHHPED 100 VEPALRKTLT 110 DLQLEYLDLY 120 LMHWPYAFER 130 GDNPFPKNAD 140 GTVRYDSTHY 150 KETWKALEVL 160 VAKGLVRALG 170 LSNFSSRQID 180 DVLSVASVRP 190 AVLQVESHPY 200 LAQNELIAHC 210 QAHGLEVTAY 220 SPLGSSDRAW 230 RHPDEPILLE 240 DPLVLALAEK 250 YGRSPAQILL 260 RWQVQRKVIC 270 IPKSVTPSRI 280 LENIQVFDFT 290 FNPEEMKQLD 300 ALNKNWRYIV 310 PMITVDGKRV 320 PRDAGHPLYP FNDPY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0005829 cytosol
Cellular Component GO:0045202 synapse
Molecular Function GO:0004032 aldose reductase (NADPH) activity
Molecular Function GO:0047655 allyl-alcohol dehydrogenase activity
Molecular Function GO:0047941 glucuronolactone reductase activity
Molecular Function GO:0047939 L-glucuronate reductase activity
Molecular Function GO:0080007 S-nitrosoglutathione reductase (NADH) activity
Biological Process GO:0046185 aldehyde catabolic process
Biological Process GO:0110095 cellular detoxification of aldehyde
Biological Process GO:0019640 D-glucuronate catabolic process to D-xylulose 5-phosphate
Biological Process GO:0044597 daunorubicin metabolic process
Biological Process GO:0044598 doxorubicin metabolic process
Biological Process GO:0019853 L-ascorbic acid biosynthetic process

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.