Search Results
Overview
| Uniprot ID | H0VNX9 |
|---|---|
| Protein Name | Tyrosine-protein phosphatase non-receptor type |
| Gene Name | PTPN11 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 237 | SRVRELSKLAETTDK |
Function
No function data available.
Protein Sequence
10
GTARRSAWFH
20
PNITGVEAEN
30
LLLTRGVDGS
40
FLARPSKSNP
50
GDFTLSVRRN
60
GAVTHIKIQN
70
TGDYYDLYGG
80
EKFATLAELV
90
QYYMEHHGQL
100
KEKNGDVIEL
110
KYPLNCADPT
120
SERWFHGHLS
130
GKEAEKLLTE
140
KGKHGSFLVR
150
ESQSHPGDFV
160
LSVRTGDDKG
170
ESNDGKSKVT
180
HVMIRCQELK
190
YDVGGGERFD
200
SLTDLVEHYK
210
KNPMVETLGT
220
VLQLKQPLNT
230
TRINAAEIES
240
RVRELSKLAE
250
TTDKVKQGFW
260
EEFETLQQQE
270
CKLLYSRKEG
280
QRQENKNKNR
290
YKNILPFDHT
300
RVVLHDGDPN
310
EPVSDYINAN
320
IIMPEFETKC
330
NNSKPKKSYI
340
ATQGCLQNTV
350
NDFWRMVFQE
360
NSRVIVMTTK
370
EVERGKSKCV
380
KYWPDEYALK
390
EYGVMRVRNV
400
KESAAHDYTL
410
RELKLSKVGQ
420
GNTERTVWQY
430
HFRTWPDHGV
440
PSDPGEVHHK
450
QESIVDAGPV
460
VVHCSAGIGR
470
TGTFIVIDIL
480
IDIIREKGVD
490
CDIDVPKTIQ
500
MVRSQRSGMV
510
QTEAQYRFIY
520
MAVQHYIETL
530
QRRIEEEQKS
540
KRKGHEYTNI
550
KYSLADQTGG
560
DQSPLPPCTP
570
TPPCAEMRED
580
SARVYENVGL
MQQQKSFR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0005158 | insulin receptor binding |
| Molecular Function | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity |
| Molecular Function | GO:0051428 | peptide hormone receptor binding |
| Molecular Function | GO:0001784 | phosphotyrosine residue binding |
| Molecular Function | GO:0030971 | receptor tyrosine kinase binding |
| Molecular Function | GO:0030159 | signaling receptor complex adaptor activity |
| Biological Process | GO:0036302 | atrioventricular canal development |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:0019221 | cytokine-mediated signaling pathway |
| Biological Process | GO:0048013 | ephrin receptor signaling pathway |
| Biological Process | GO:0038127 | ERBB signaling pathway |
| Biological Process | GO:0060325 | face morphogenesis |
| Biological Process | GO:0008543 | fibroblast growth factor receptor signaling pathway |
| Biological Process | GO:0048806 | genitalia development |
| Biological Process | GO:0048839 | inner ear development |
| Biological Process | GO:0033629 | negative regulation of cell adhesion mediated by integrin |
| Biological Process | GO:0032331 | negative regulation of chondrocyte differentiation |
| Biological Process | GO:1902564 | negative regulation of neutrophil activation |
| Biological Process | GO:0042130 | negative regulation of T cell proliferation |
| Biological Process | GO:0050860 | negative regulation of T cell receptor signaling pathway |
| Biological Process | GO:0032480 | negative regulation of type I interferon production |
| Biological Process | GO:0046326 | positive regulation of D-glucose import across plasma membrane |
| Biological Process | GO:0070374 | positive regulation of ERK1 and ERK2 cascade |
| Biological Process | GO:0046628 | positive regulation of insulin receptor signaling pathway |
| Biological Process | GO:0032728 | positive regulation of interferon-beta production |
| Biological Process | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway |
| Biological Process | GO:0045778 | positive regulation of ossification |
| Biological Process | GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0032760 | positive regulation of tumor necrosis factor production |
| Biological Process | GO:0043254 | regulation of protein-containing complex assembly |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.