Search Results

Overview

Uniprot IDH0VPQ3
Protein NameWW domain-binding protein 4
Gene NameWBP4
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
293 EKSKTLKKSNPYGEW
359 DGVAPVFKKRRIENG

Function

Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex

Protein Sequence

10 MKLKADYWKS 20 QPKKFCDYCK 30 CWIADNRPSV 40 EFHERGKNHK 50 ENVAKRISEI 60 KQKSLDKAKE 70 EEKASKEFAA 80 MEAAALKAYQ 90 EDLKRLASLP 100 FSHFFLDTSV 110 PSVSPVPSTT 120 PPPPASNQPK 130 EKKKKKKDPS 140 KGRWVEGVTS 150 EGYCYYYDLI 160 TGASQWEKPE 170 GFQGNLKKTA 180 AKAIWVEGLS 190 EDGYSYYYNT 200 ETGESKWEKP 210 DDFIPHTGSM 220 PSSKVDEKPV 230 GTLEESESSD 240 SKSDGEQDSK 250 GEVSTETKQL 260 KIKFKEKNKN 270 SVEEKAPKIQ 280 KEKSVQKQNS 290 SGPNEEKSKT 300 LKKSNPYGEW 310 QEIKQEIKSD 320 EEVDLELPST 330 DNEYVSTSEA 340 DTVEPKVIFK 350 EKTVTSLGVV 360 ADGVAPVFKK 370 RRIENGKSRN LRQRGDDQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0071005 U2-type precatalytic spliceosome
Molecular Function GO:0070064 proline-rich region binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0045292 mRNA cis splicing, via spliceosome

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.