Search Results
Overview
| Uniprot ID | H0VSF4 |
|---|---|
| Protein Name | Zinc finger protein 512B |
| Gene Name | ZNF512B |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 197 | SKPIGVSKPVTIGKP |
| 209 | GKPVGVSKPIGISKP |
Function
Involved in transcriptional regulation by repressing gene expression. Associates with the nucleosome remodeling and histone deacetylase (NuRD) complex, which promotes transcriptional repression by histone deacetylation and nucleosome remodeling. Sequence-specific DNA-binding protein that recognizes repetitive and non-consecutive TTC sequences in pericentric repeat and initiate heterochromatin formation through interaction with SUV39H1/2 methyltransferases which catalyze histone H3K9 methylation
Protein Sequence
10
MTDPFCVGGG
20
RRLQGSSKSG
30
PGKGSSRKEV
40
QLPMLQDPPK
50
LGMPVVHSGQ
60
TVPGQAPLCF
70
DPGSPASDRT
80
EGKKKGRPKA
90
ENQALRDIPL
100
SLMNQWKDEF
110
KAHSRVKCPN
120
SGCWLEFPSI
130
YGLKYHYQRC
140
QGGAISDRLA
150
FPCPFCEAAF
160
TSKTQLEKHR
170
IWNHMDHPLP
180
TPKPGPVSRP
190
VTISRPVGVS
200
KPIGVSKPVT
210
IGKPVGVSKP
220
IGISKPVTVT
230
RPIPVTKAMP
240
VTRPVPLTKP
250
IPVTKPVPVT
260
KSMPVTKLVT
270
VTKPVPVNKP
280
MPVSRPIVVS
290
KPVPVNRPVA
300
ISRHTPPCKM
310
VLLTKSENKV
320
PRATGKSSSK
330
KRAADSLDTF
340
PIPPKQARPE
350
NGEYGPSTTG
360
QSAAFQLSTN
370
PSGSRPSMGK
380
EVLRPTGPVS
390
LPEEDPERTK
400
HRRKQKTPKK
410
FTGEQPSISG
420
TFGLKGLVKA
430
EDKARVHRSK
440
KLEGPGPEDM
450
RKKVPATSIP
460
VSKEIPTPVT
470
HPAPGGPEEQ
480
WQRAIHERGE
490
AICPTCNVVT
500
RKTLVGLKKH
510
MEVCQKLQDA
520
LKCQHCRKQF
530
KSKAGLNYHT
540
MAEHSAKPTD
550
AEASEGSEQE
560
ERERLRKVLK
570
QMGRLRCPQE
580
GCGAAFSSLM
590
GYQYHQRRCG
600
KPPCEVDSPS
610
FPCTHCGKTY
620
RSKAGHDYHV
630
RSEHTAPPPE
640
ESMDKTSEAE
650
DLLGVERTPS
660
GRIRRTSAQV
670
AVFHLQEIAE
680
DELARDWTKR
690
RMKDDLVPES
700
ARLNYTRPGL
710
PALNPQLLEV
720
WKNEVKEKGH
730
VNCPNDCCEA
740
IYSSVSGLKA
750
HLASCSKGDH
760
LVGKYHCLLC
770
PKEFSSESGV
780
KYHILKTHAE
790
NWFRTSADPP
800
PKHRSQDSLS
810
PRREKKKSLV
820
GGKKRGRKPK
830
ERPPEEPVPK
840
LPPRRDDWSL
850
GGRDKGARGS
860
TGRKVGAGKT
TEK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.