Search Results

Overview

Uniprot ID	H0VUC7
Protein Name	Peptidylprolyl isomerase domain and WD repeat-containing protein 1
Gene Name	PPWD1
Organism	Cavia porcellus

Kla Sites from experimental identification

Position	Flanking peptide
63	ATLAKKRKVLEFERV

Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be involved in pre-mRNA splicing

Protein Sequence

10 MAAESGSDSR 20 VRGRRRRDTE 30 DPEKSEFSEK 40 ELAVGLAQEN 50 VEENEERWVG 60 PLPVEATLAK 70 KRKVLEFERV 80 YLDNLPSASM 90 YERSYMHRDV 100 ITHVVCTKTD 110 FIITASHDGH 120 VKFWKKIEEG 130 IEFVKHFRSH 140 LGVIESIAVS 150 SEGALFCSVG 160 DDKAMKVFDV 170 VNFDMINMLK 180 LGYFPGQCEW 190 IYCPGDAISS 200 VAASEKSTGK 210 IFIYDGRGDN 220 QPLHVFDKLH 230 TSPLTQIRLN 240 PVYKAVVSSD 250 KSGMIEYWTG 260 PPHEYKFPRN 270 VNWEYKTDTD 280 LYEFAKCKAY 290 PTSICFSPDG 300 KKIATIGSDR 310 KVRIFRFLTG 320 KLMRVFDESL 330 SMFTELQQMR 340 QQLPDMEFGR 350 RMAVERELEK 360 VDAVRLINIV 370 FDETGYFVLY 380 GTMLGIKVIN 390 VETNRCVRIL 400 GKQENIRVMQ 410 LALFQGIAKK 420 HRAATTIEMK 430 ASENPVLQNI 440 QADPTIVCTS 450 FKKNRFYMFT 460 RREPEDTKSA 470 DSDRDVFNEK 480 PSKEEVMAAT 490 QAEGPKRVSD 500 SAIIHTSMGD 510 IHIKLFPVEC 520 PKTVENFCVH 530 SRNGYYNGHT 540 FHRIIKGFMI 550 QTGDPTGTGM 560 GGESIWGGEF 570 EDEFHSTLRH 580 DRPYTLSMAN 590 AGSNTNGSQF 600 FITVVPTPWL 610 DNKHTVFGRV 620 TKGMEVVQRI 630 SNVKVNPKTD 640 KPYEDVSIIN ITVK

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0071013	catalytic step 2 spliceosome
Cellular Component	GO:0016604	nuclear body
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
Biological Process	GO:0006397	mRNA processing
Biological Process	GO:0008380	RNA splicing

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.