Search Results
Overview
| Uniprot ID | H0VXN4 |
|---|---|
| Protein Name | Peptidyl-prolyl cis-trans isomerase |
| Gene Name | Ppia |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 125 | KTEWLDGKHVVFGKV |
| 131 | GKHVVFGKVKEGMNT |
| 133 | HVVFGKVKEGMNTVE |
| 155 | RNGKTSKKITITDCG |
| 28 | SFELYADKVPKTAEN |
| 31 | LYADKVPKTAENFRA |
| 44 | RALSTGEKGFGYKGS |
| 49 | GEKGFGYKGSCFHRI |
| 82 | GKSIYGEKFDDENFI |
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Protein Sequence
10
MVNPTVFFDI
20
AADGEPLGRV
30
SFELYADKVP
40
KTAENFRALS
50
TGEKGFGYKG
60
SCFHRIIPGF
70
MCQGGDFTRH
80
NGTGGKSIYG
90
EKFDDENFIL
100
KHTGPGILSM
110
ANAGPNTNGS
120
QFFICTAKTE
130
WLDGKHVVFG
140
KVKEGMNTVE
150
AMERFGSRNG
160
KTSKKITITD
CGQL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0016018 | cyclosporin A binding |
| Molecular Function | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity |
| Biological Process | GO:0006915 | apoptotic process |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.