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Overview

Uniprot IDH0W4J5
Protein NameSmall ribosomal subunit protein uS11
Gene NameRPS14
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
106 ATGGNRTKTPGPGAQ

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MAPRKGKEKK 20 EEQVISLGPQ 30 VAEGENVFGV 40 CHIFASFNDT 50 FVHVTDLSGK 60 ETICRVTGGM 70 KVKADRDESS 80 PYAAMLAAQD 90 VAQRCKELGI 100 TALHIKLRAT 110 GGNRTKTPGP 120 GAQSALRALA 130 RSGMKIGRIE 140 DVTPIPSDST 150 RRKGGRRGRR L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0022627 cytosolic small ribosomal subunit
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0014069 postsynaptic density
Cellular Component GO:0032040 small-subunit processome
Molecular Function GO:0048027 mRNA 5'-UTR binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0030218 erythrocyte differentiation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0042274 ribosomal small subunit biogenesis

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.