Overview
| Uniprot ID | H0W4J5 |
| Protein Name | Small ribosomal subunit protein uS11 |
| Gene Name | RPS14 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 106 |
ATGGNRTKTPGPGAQ |
Function
Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome
Protein Sequence
10
MAPRKGKEKK
20
EEQVISLGPQ
30
VAEGENVFGV
40
CHIFASFNDT
50
FVHVTDLSGK
60
ETICRVTGGM
70
KVKADRDESS
80
PYAAMLAAQD
90
VAQRCKELGI
100
TALHIKLRAT
110
GGNRTKTPGP
120
GAQSALRALA
130
RSGMKIGRIE
140
DVTPIPSDST
150
RRKGGRRGRR
L
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0022627 |
cytosolic small ribosomal subunit |
| Cellular Component |
GO:0005783 |
endoplasmic reticulum |
| Cellular Component |
GO:0014069 |
postsynaptic density |
| Cellular Component |
GO:0032040 |
small-subunit processome |
| Molecular Function |
GO:0048027 |
mRNA 5'-UTR binding |
| Molecular Function |
GO:0003735 |
structural constituent of ribosome |
| Biological Process |
GO:0002181 |
cytoplasmic translation |
| Biological Process |
GO:0030218 |
erythrocyte differentiation |
| Biological Process |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
| Biological Process |
GO:0042274 |
ribosomal small subunit biogenesis |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.