Search Results
Overview
| Uniprot ID | H0W639 |
|---|---|
| Protein Name | Dihydropyrimidinase-related protein 2 |
| Gene Name | DPYSL2 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 472 | SGRYVPRKPFPDFVY |
| 480 | PFPDFVYKRIKARSR |
Function
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis
Protein Sequence
10
MSYQGKKNIP
20
RITSDRLLIK
30
GGKIVNDDQS
40
FYADIYMEDG
50
LIKQIGENLI
60
VPGGVKTIEA
70
HSRMVIPGGI
80
DVHTRFQMPD
90
QGMTSADDFF
100
QGTKAALAGG
110
TTMIIDHVVP
120
EPGTSLLAAF
130
DQWREWADSK
140
SCCDYSLHVD
150
ITEWHKGIQE
160
EMEALVKDHG
170
VNSFLVYMAF
180
KDRFQLTDSQ
190
IYEVLSVIRD
200
IGAIAQVHAE
210
NGDIIAEEQQ
220
RILDLGITGP
230
EGHVLSRPEE
240
VEAEAVNRSI
250
TIANQTNCPL
260
YITKVMSKSA
270
AEVIAQARKK
280
GTVVYGEPIT
290
ASLGTDGSHY
300
WSKNWAKAAA
310
FVTSPPLSPD
320
PTTPDFLSSL
330
LSCGDLQVTG
340
SAHCTFNTAQ
350
KAVGKDNFTL
360
IPEGTNGTEE
370
RMSVIWDKAV
380
VTGKMDENQF
390
VAVTSTNAAK
400
VFNLYPRKGR
410
IAVGSDADLV
420
IWDPDSMKTI
430
SAKTHNSALE
440
YNIFEGMECR
450
GSPLVVISQG
460
KIVLEDGTLH
470
VTEGSGRYVP
480
RKPFPDFVYK
490
RIKARSRAQI
500
DDNIPRRTTQ
510
RIVAPPGGRA
NITSLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0045171 | intercellular bridge |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0098685 | Schaffer collateral - CA1 synapse |
| Molecular Function | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.