Search Results
Overview
| Uniprot ID | H0W6G0 |
|---|---|
| Protein Name | Synapse-associated protein 1 |
| Gene Name | SYAP1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 189 | MRFALVPKLVKEEVF |
Function
Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation
Protein Sequence
10
MFRGLSSWLG
20
LQSPGTDGEA
30
SAGDPPPEQH
40
SEVAAQPTKE
50
QQPEDLELLH
60
QARDLGNYLF
70
NFASAATKKI
80
TESVAETAQT
90
IKKSVEEGKI
100
DDIIDKTIIG
110
DFQKEQKKFV
120
EEQHTKKSEA
130
AVPPWVDSND
140
EETIQQQILA
150
LAADKRNFLR
160
DPPVGVQFHF
170
DFDQMYPVAL
180
VMLREDELLS
190
KMRFALVPKL
200
VKEEVFWRNY
210
FYRVSLIKQS
220
AQLTALAAQQ
230
ASGKEDKKGS
240
MSAKSPLTEN
250
DEEEISTSPG
260
VSEFVSDAFD
270
ACNLNQEDLR
280
KEMEQLVLDK
290
KEEETAVLEE
300
DSADWEKELQ
310
QELQEYEVVT
320
ESDKRDENWD
330
KEIEKMLQET
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0045202 | synapse |
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:0032869 | cellular response to insulin stimulus |
| Biological Process | GO:0045600 | positive regulation of fat cell differentiation |
| Biological Process | GO:0048172 | regulation of short-term neuronal synaptic plasticity |
| Biological Process | GO:0038203 | TORC2 signaling |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.