Search Results
Overview
| Uniprot ID | H0W8B0 |
|---|---|
| Protein Name | Small nuclear ribonucleoprotein Sm D2 |
| Gene Name | SNRPD2 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 9 | KSLLNKPKSEMTPEE |
Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs
Protein Sequence
10
MKSLLNKPKS
20
EMTPEELQKR
30
EEEEFNTGPL
40
SVLTQSVKNN
50
TQVLINCRNN
60
KKLLGRVKAF
70
DRHCNMVLEN
80
VKEMWTEVPK
90
SGKGKKKSKP
100
VNKDRYISKM
110
FLRGDSVIVV
LRNPLIAGK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0097525 | spliceosomal snRNP complex |
| Cellular Component | GO:0005689 | U12-type spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.