Search Results

Overview

Uniprot IDH0W8D8
Protein NameProtein FRG1
Gene NameFrg1
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
211 CEINYVKKFQSFQDH

Function

Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B

Protein Sequence

10 MAEYSYVKST 20 KLVLKGTKAK 30 SKKKKKEKKR 40 KNEEDEETQL 50 DIVGIWWTVA 60 NFGDISGTIA 70 IEMDKGTYIH 80 ALDNGLFTLG 90 APHKEVDEGP 100 SPPEQFTAVK 110 LSDSRIALKS 120 GYGKYLGINS 130 DGLVVGRSDA 140 IGPREQWEPV 150 FQDGKMALLA 160 SNSCFIRCNE 170 AGDIEAKSKT 180 AGEEEMIKIR 190 SCAERETKKK 200 DDIPEEDKGN 210 VKQCEINYVK 220 KFQSFQDHKL 230 KISKEDSKIL 240 KKARKDGFLH 250 ETLLDRRAKL KADRYCK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015030 Cajal body
Cellular Component GO:0071013 catalytic step 2 spliceosome
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0055120 striated muscle dense body
Cellular Component GO:0030018 Z disc
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0007517 muscle organ development
Biological Process GO:0006364 rRNA processing

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.