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Overview

Uniprot IDH0W958
Protein NameEndophilin-A2
Gene NameSH3GL1
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
76 TMLNTVSKIRGQVKN

Function

Implicated in endocytosis. May recruit other proteins to membranes with high curvature

Protein Sequence

10 MSVAGLKKQF 20 YKASQLVSEK 30 VGGAEGTKLD 40 DDFKEMEKKV 50 DVTSKAVAEV 60 LVRTIEYLQP 70 NPASRAKLTM 80 LNTVSKIRGQ 90 VKNPGYPQSE 100 GLLGECMVRH 110 GRELGGESNF 120 GDALLDAGES 130 MKRLAEVKDS 140 LDIEVKQNFI 150 DPLQNLCDKD 160 LKEIQHHLKK 170 LEGRRLDFDY 180 KKKRQGKIPD 190 EELRQASEKF 200 EESKEVAETS 210 MHNLLETDVE 220 QVSQLSALVD 230 AQLDYHRQAV 240 QILEELAEKL 250 KRRVREASSR 260 PRREYKPKPR 270 EPYDLGEPEQ 280 SNGGFPCAPA 290 PKATAPSSSS 300 FRSSDNKPIR 310 TPSRSMPPLD 320 QPSCKALYDF 330 EPENDGELGF 340 HEGDVITLTN 350 QIAKNRYEVY VEVLVPLPQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0031901 early endosome membrane
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0002102 podosome
Cellular Component GO:0098793 presynapse
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0008289 lipid binding
Biological Process GO:0016191 synaptic vesicle uncoating

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.