Search Results
Overview
| Uniprot ID | H0WC22 |
|---|---|
| Protein Name | Heterogeneous nuclear ribonucleoprotein A0 |
| Gene Name | HNRNPA0 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 133 | KAEIIADKQSGKKRG |
| 159 | ADKAAVVKFHPIQGH |
| 176 | EVKKAVPKEDIHAGG |
Function
mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs
Protein Sequence
10
MENSQLCKLF
20
IGGLNVQTSE
30
SGLRGHFEAF
40
GTLTDCVVVV
50
NPQTKRSRCF
60
GFVTYSNVEE
70
ADAAMAASPH
80
AVDGNTVELK
90
RAVSREDSAR
100
PGAHAKVKKL
110
FVGGLKGDVA
120
EGDLIEHFSQ
130
FGAVEKAEII
140
ADKQSGKKRG
150
FGFVYFQNHD
160
AADKAAVVKF
170
HPIQGHRVEV
180
KKAVPKEDIH
190
AGGGGGGSRS
200
SRGGRGGRGR
210
GGGRDQNGLS
220
KGGGGGYNSY
230
GGYGGGGGYN
240
AYGGGGGGSS
250
YGGSDYGNGF
260
GGFGSYSQHQ
270
SSYGPMKSGG
280
GGGGSSWGGR
290
SNSGPYRGGY
300
GGGGGYGGSS
F
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0035925 | mRNA 3'-UTR AU-rich region binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0070935 | 3'-UTR-mediated mRNA stabilization |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0032496 | response to lipopolysaccharide |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.