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Overview

Uniprot IDI1KTM3
Protein NameADP/ATP translocase
Gene NameLOC100819556
OrganismGlycine max

Kla Sites from experimental identification

Position Flanking peptide
124 QNQDEMIKTGRLSEP

Function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane

Protein Sequence

10 MLDQVQHPTI 20 MDKVAGQLHL 30 RSGVSGIRSY 40 EGAYCHPTMY 50 QRPSFGNYSN 60 AALQYPVMPS 70 CKATMDLSAA 80 ATTASPVFVA 90 APAEKGHFLI 100 DFLMGGVSAA 110 VSKTAAAPIE 120 RVKLLIQNQD 130 EMIKTGRLSE 140 PYKGIGDCFK 150 RTMADEGVVS 160 LWRGNTANVI 170 RYFPTQALNF 180 AFKDYFKRLF 190 NFKKDRDGYW 200 KWFAGNLASG 210 GAAGASSLLF 220 VYSLDYARTR 230 LANDAKAAKK 240 GGERQFNGLV 250 DVYRKTLASD 260 GVAGLYRGFN 270 ISCVGIIVYR 280 GLYFGLYDSV 290 KPVVLTGSLQ 300 DSFFASFALG 310 WLITNGAGLA 320 SYPIDTVRRR 330 MMMTSGEAVK 340 YKSSLDAFTQ 350 ILKNEGAKSL 360 FKGAGANILR 370 AVAGAGVLAG 380 YDKLQVLVFG KKYGSGGA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Molecular Function GO:0005471 ATP:ADP antiporter activity
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:0046902 regulation of mitochondrial membrane permeability

Reference

[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.