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Overview

Uniprot IDI1M3R5
Protein NameADP/ATP translocase
Gene NameLOC100780671
OrganismGlycine max

Kla Sites from experimental identification

Position Flanking peptide
322 AFKIIVAKEGTKSLF

Function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane

Protein Sequence

10 MADGLHSRHP 20 SVVQKLSGQS 30 YLLSRLAPTH 40 SRNYSTTGSY 50 FNGGLQSSGL 60 VPVMAHAPAE 70 KGVSGFLLDF 80 MMGGVSAAVS 90 KTAAAPIERV 100 KLLIQNQDEM 110 IKSGRLSEPY 120 KGIGDCFSRT 130 MKDEGVIALW 140 RGNTANVIRY 150 FPTQALNFAF 160 KDYFKRLFNF 170 KKDKDGYWKW 180 FAGNLASGGA 190 AGASSLLFVY 200 SLDYARTRLA 210 NDAKAAKKGG 220 ERQFNGLVDV 230 YRKTIKSDGI 240 AGLYRGFNIS 250 CVGIIVYRGL 260 YFGMYDSLKP 270 VVLVGGLQDS 280 FFASFLLGWG 290 ITIGAGLASY 300 PIDTVRRRMM 310 MTSGEAVKYK 320 SSLEAFKIIV 330 AKEGTKSLFK 340 GAGANILRAV 350 AGAGVLAGYD 360 KLQLILFGKK YGSGGGG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Molecular Function GO:0005471 ATP:ADP antiporter activity
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:0046902 regulation of mitochondrial membrane permeability

Reference

[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.