Search Results
Overview
| Uniprot ID | I1M6P8 |
|---|---|
| Protein Name | dihydrolipoyllysine-residue succinyltransferase |
| Gene Name | LOC100813488 |
| Organism | Glycine max |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 195 | GAPQPTQKVSEEKKA |
Function
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
Protein Sequence
10
MFGVVRRRVA
20
SGSPSPWLLG
30
QSVQNIRSGP
40
SVSARASSIA
50
VKEIAFPSGG
60
CGFVRNFSHI
70
TLGSWINSKP
80
MRVVIHPEAT
90
VQTLGRLFSS
100
ESGDTVDVVV
110
PPLAESISDG
120
TLAQFLKRPG
130
DRVNADEPIA
140
QIETDKVTID
150
VSSPESGVIL
160
KLLANEGDTV
170
EPGNKIAIIS
180
RSADATHVAP
190
SETTSEKGAP
200
QPTQKVSEEK
210
KAPKVETAPA
220
KEKPKAPPAI
230
LKSPTEPQLP
240
PKERERRVPM
250
TRLRKRVATR
260
LKDSQNTFAM
270
LTTFNEVDMT
280
NLMKLRSDYK
290
DAFVEKHGVK
300
LGLMSGFVKA
310
AVNALQHQPI
320
VNAVIDGDDI
330
IYRDYIDISI
340
AVGTSKGLVV
350
PVIRNADTMN
360
FADIEKQINA
370
FAKKANDGTL
380
SIDEMAGGTL
390
TISNGGVYGS
400
LLSTPIINPP
410
QSAILGMHSI
420
VSRPTVVGGN
430
IVPRPLMYVA
440
LTYDHRIIDG
450
REAVFFLRRI
460
KDIVEDPRRL
LLDI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045252 | oxoglutarate dehydrogenase complex |
| Molecular Function | GO:0004149 | dihydrolipoyllysine-residue succinyltransferase activity |
| Biological Process | GO:0033512 | L-lysine catabolic process to acetyl-CoA via L-saccharopine |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.