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Overview

Uniprot IDI1MJN2
Protein NameADP/ATP translocase
Gene NameLOC100789942
OrganismGlycine max

Kla Sites from experimental identification

Position Flanking peptide
125 QNQDEMIKTGRLSEP

Function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane

Protein Sequence

10 MVDQVQHPTI 20 MDKVAGQLHL 30 RSGLSSGIRS 40 YDGAYRHPAM 50 YQRPSFGNYS 60 NAALQFPVMP 70 TCKATMDLSA 80 TATSASPVFV 90 AAPAEKGHFL 100 LDFLMGGVSA 110 AVSKTAAAPI 120 ERVKLLIQNQ 130 DEMIKTGRLS 140 EPYKGIGDCF 150 KRTMADEGAI 160 SLWRGNTANV 170 IRYFPTQALN 180 FAFKDYFKRL 190 FNFKKDRDGY 200 WKWFAGNLAS 210 GGAAGASSLL 220 FVYSLDYART 230 RLANDAKAAK 240 KGGERQFNGL 250 VDVYRKTLAS 260 DGVAGLYRGF 270 NISCVGIIVY 280 RGLYFGLYDS 290 VKPVVLTGSL 300 QDSFFASFAL 310 GWLITNGAGL 320 ASYPIDTVRR 330 RMMMTSGEAV 340 KYKSSLDAFT 350 QILKNEGAKS 360 LFKGAGANIL 370 RAVAGAGVLA 380 GYDKLQVLVF GKKYGSGGA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Molecular Function GO:0005471 ATP:ADP antiporter activity
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:0046902 regulation of mitochondrial membrane permeability

Reference

[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.