Search Results

Overview

Uniprot ID	I3L6F0
Protein Name	Poly(A) polymerase
Gene Name	PAPOLA
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
617	PSGNAATKIPNPIVG

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's

Protein Sequence

10 MPFPVTTQGS 20 QQTQPPQKHY 30 GITSPISLAA 40 PKETDCLLTQ 50 KLIETLKPFG 60 VFEEEEELQR 70 RILILGKLNN 80 LVKEWIREIS 90 ESKNLPQSVI 100 ENVGGKIFTF 110 GSYRLGVHTK 120 GADIDALCVA 130 PRHVDRSDFF 140 TSFYDKLKLQ 150 EEVKDLRIDI 160 LFARLALQTI 170 PEDLDLRDDS 180 LLKNLDIRCI 190 RSLNGCRVTD 200 EILHLVPNID 210 NFRLTLRAIK 220 LWAKRHNIYS 230 NILGFLGGVS 240 WAMLVARTCQ 250 LYPNAIASTL 260 VHKFFLVFSK 270 WEWPNPVLLK 280 QPEECNLNLP 290 VWDPRVNPSD 300 RYHLMPIITP 310 AYPQQNSTYN 320 VSVSTRMVMV 330 EEFKQGLAIT 340 DEILLSKAEW 350 SKLFEAPNFF 360 QKYKHYIVLL 370 ASAPTEKQRL 380 EWVGLVESKI 390 RILVGSLEKN 400 EFITLAHVNP 410 QSFPAPKENP 420 DKEEFRTMWV 430 IGLVFKKTEN 440 SENLSVDLTY 450 DIQSFTDTVY 460 RQAINSKMFE 470 VDMKIAAMHV 480 KRKQLHQLLP 490 NHVLQKKKKH 500 STDGVRLTPL 510 NDSSLDLSMD 520 SDNSMSVPSP 530 TSAMKTSPLN 540 SSGSSQGRNS 550 PAPAVTAASV 560 TNIQATEVSV 570 PQVNSSESSG 580 GTSSESIPQT 590 ATQPAISPPP 600 KPTVSRVVSS 610 TRLVNPPPRP 620 SGNAATKIPN 630 PIVGVKRTSS 640 PHKEESPKKT 650 RTEEEQLDTE 660 TSTTQSETIQ 670 TAASLLASQK 680 TSSTDLSDIP 690 ALPANPIPVI 700 KNSIKLRLNR

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0046872	metal ion binding
Molecular Function	GO:1990817	poly(A) RNA polymerase activity
Molecular Function	GO:0003723	RNA binding
Biological Process	GO:0006397	mRNA processing
Biological Process	GO:0031123	RNA 3'-end processing

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.