Search Results
Overview
| Uniprot ID | I3L6X7 |
|---|---|
| Protein Name | Vacuolar-sorting protein SNF8 |
| Gene Name | SNF8 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | VGAGAIAKKKLAEAK |
| 20 | KKKLAEAKYKERGTV |
Function
Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs
Protein Sequence
10
MHRRGVGAGA
20
IAKKKLAEAK
30
YKERGTVLAE
40
DQLAQMSKQL
50
DMFKTNLEEF
60
ASKHKQEIRK
70
NPEFRVQFQD
80
MCATIGVDPL
90
ASGKGFWSEM
100
LGVGDFYYEL
110
GVQIIEVCLA
120
LKHRNGGLIT
130
LEELHQQVLK
140
GRGKFAQDVS
150
QDDLIRAIKK
160
LKALGTGFSI
170
IPVGGTYLIQ
180
SVPAELNMDH
190
TVVLQLAEKN
200
GYVTVSDIKA
210
SLKWETERAR
220
QVLEHLLKEG
230
LAWLDLQAPG
240
EAHYWLPALF
250
TDLYSQEITA
EEAREALP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0000814 | ESCRT II complex |
| Cellular Component | GO:0031902 | late endosome membrane |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0055037 | recycling endosome |
| Cellular Component | GO:0005667 | transcription regulator complex |
| Molecular Function | GO:0016247 | channel regulator activity |
| Molecular Function | GO:0008289 | lipid binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0045022 | early endosome to late endosome transport |
| Biological Process | GO:0032456 | endocytic recycling |
| Biological Process | GO:0016236 | macroautophagy |
| Biological Process | GO:0036258 | multivesicular body assembly |
| Biological Process | GO:1903543 | positive regulation of exosomal secretion |
| Biological Process | GO:0010628 | positive regulation of gene expression |
| Biological Process | GO:0045732 | positive regulation of protein catabolic process |
| Biological Process | GO:0043328 | protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| Biological Process | GO:0061635 | regulation of protein complex stability |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.