Search Results
Overview
| Uniprot ID | I3L742 |
|---|---|
| Protein Name | RuvB-like helicase |
| Gene Name | RUVBL1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 162 | SHVVIGLKTAKGTKQ |
| 281 | KLRGEINKVVNKYID |
| 7 | *MKIEEVKSTTKTQR |
Function
Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding
Protein Sequence
10
MKIEEVKSTT
20
KTQRIASHSH
30
VKGLGLDENG
40
LAKQAASGLV
50
GQENAREACG
60
VIVELIKSKK
70
MAGRAVLLAG
80
PPGTGKTALA
90
LAIAQELGSK
100
VPFCPMVGSE
110
VYSTEIKKTE
120
VLMENFRRAI
130
GLRIKETKEV
140
YEGEVTELTP
150
CETENPMGGY
160
GKTISHVVIG
170
LKTAKGTKQL
180
KLDPSIFESL
190
QKERVEAGDV
200
IYIEANSGAV
210
KRQGRCDTYA
220
TEFDLEAEEY
230
VPLPKGDVHK
240
KKEIIQDVTL
250
HDLDVANARP
260
QGGQDILSMM
270
GQLMKPKKTE
280
ITDKLRGEIN
290
KVVNKYIDQG
300
VAELVPGVLF
310
VDEVHMLDIE
320
CFTYLHRALE
330
SSIAPIVIFA
340
SNRGNCVIRG
350
TEDITSPHGI
360
PLDLLDRVMI
370
IRTMLYTPQE
380
MKQIIKIRAQ
390
TEGINISEEA
400
LNHLGEIGTK
410
TTLRYSVQLL
420
TPANLLAKIN
430
GKDGIEKEHV
440
EEISELFYDA
450
KSSAKILADQ
460
QDTGQAGPNL
ACG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0036064 | ciliary basal body |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0120293 | dynein axonemal particle |
| Cellular Component | GO:0031011 | Ino80 complex |
| Cellular Component | GO:0071339 | MLL1 complex |
| Cellular Component | GO:0035267 | NuA4 histone acetyltransferase complex |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0097255 | R2TP complex |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0000812 | Swr1 complex |
| Molecular Function | GO:0043531 | ADP binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0051117 | ATPase binding |
| Molecular Function | GO:0003678 | DNA helicase activity |
| Molecular Function | GO:0017025 | TBP-class protein binding |
| Molecular Function | GO:0001094 | TFIID-class transcription factor complex binding |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Biological Process | GO:0006338 | chromatin remodeling |
| Biological Process | GO:0006310 | DNA recombination |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| Biological Process | GO:1905168 | positive regulation of double-strand break repair via homologous recombination |
| Biological Process | GO:1904507 | positive regulation of telomere maintenance in response to DNA damage |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0006275 | regulation of DNA replication |
| Biological Process | GO:0060382 | regulation of DNA strand elongation |
| Biological Process | GO:0045995 | regulation of embryonic development |
| Biological Process | GO:0000723 | telomere maintenance |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.