Search Results
Overview
| Uniprot ID | I3L7Z6 |
|---|---|
| Protein Name | Protein S100 |
| Gene Name | S100A6 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 26 | YSGREGDKNTLSKSE |
| 31 | GDKNTLSKSELKELI |
| 35 | TLSKSELKELIQKEL |
| 40 | ELKELIQKELTIGAK |
| 47 | KELTIGAKLQDAEIA |
Function
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative
Protein Sequence
10
MACPLDQAIG
20
LLVAIFHKYS
30
GREGDKNTLS
40
KSELKELIQK
50
ELTIGAKLQD
60
AEIAKLMDDL
70
DRNKDQVVNF
80
QEYVTFLGAL
90
AMIYNDVLRG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009898 | cytoplasmic side of plasma membrane |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0001726 | ruffle |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0048306 | calcium-dependent protein binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0044548 | S100 protein binding |
| Molecular Function | GO:0005523 | tropomyosin binding |
| Molecular Function | GO:0008270 | zinc ion binding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.