Search Results
Overview
| Uniprot ID | I3L893 |
|---|---|
| Protein Name | Rab GDP dissociation inhibitor |
| Gene Name | GDI1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 247 | NGKVVGVKSEGEVAR |
| 256 | EGEVARCKQLICDPS |
| 271 | YVPDRVRKAGQVIRI |
| 90 | VEGSFVYKGGKIYKV |
Function
Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP
Protein Sequence
10
MSVNGKKVLH
20
MDRNPYYGGE
30
SSSITPLEEL
40
YKRFQLLEGP
50
PEAMGRGRDW
60
NVDLIPKFLM
70
ANGQLVKMLL
80
YTEVTRYLDF
90
KVVEGSFVYK
100
GGKIYKVPST
110
ETEALASNLM
120
GMFEKRRFRK
130
FLVFVANFDE
140
NDPKTFEGVD
150
PQSTSMRDVY
160
RKFDLGQDVI
170
DFTGHALALY
180
RTDDYLDQPC
190
LETINRIKLY
200
SESLARYGKS
210
PYLYPLYGLG
220
ELPQGFARLS
230
AIYGGTYMLN
240
KPVDDIIMEN
250
GKVVGVKSEG
260
EVARCKQLIC
270
DPSYVPDRVR
280
KAGQVIRIIC
290
ILSHPIKNTN
300
DANSCQIIIP
310
QNQVNRKSDI
320
YVCMISYAHN
330
VAAQGKYIAI
340
ASTTVETAEP
350
EKEVEPALEL
360
LEPIDQKFVA
370
ISDLYEPVDD
380
GSESQVFCSC
390
SYDATTHFET
400
TCNDIKDIYK
410
RMVGSAFDFE
420
NMKRKQNDVF
GEADQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005794 | Golgi apparatus |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005093 | Rab GDP-dissociation inhibitor activity |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0007264 | small GTPase-mediated signal transduction |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.