Search Results

Overview

Uniprot IDI3L908
Protein NameWD repeat and HMG-box DNA-binding protein 1
Gene NameWDHD1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1025 KENLNLPKKQKPLNL
208 LLAVPVEKSVKLYRR
880 NEKSPVIKPLVPKPK
889 LVPKPKSKQASAASF

Function

Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork

Protein Sequence

10 MPATQKPMRY 20 GHTEGHTDVC 30 FDDSGSCIVT 40 CGSDGDVRIW 50 EDLDDDDPKS 60 INVGEKAYSC 70 ALKNGKLVTA 80 VSNNTIQVHT 90 FPEGVPDGIL 100 TRFTTNANHV 110 IFNEDGTKIA 120 AGSSDFLVKV 130 VDVMDCSQQK 140 TFRGHDAPVL 150 SLSFDPKDIF 160 LASSSCDGSV 170 KVWQISDQTC 180 AISWPLLQKC 190 NDVINAKSIC 200 RLAWQPKSGK 210 LLAVPVEKSV 220 KLYRRETWSN 230 QFDLSDNFIS 240 QVSSRVERDY 250 NDLFDGDDTG 260 NVGDFPNDNA 270 VETHSFSKET 280 RNDEEDDDDL 290 MLASGRPRQR 300 SHILEDDENS 310 VDVTMLKTGS 320 SRLKEEEEDD 330 QAGNIHSLPL 340 ITSQKPFYDG 350 PMPTPRQKPF 360 QSGSTPLHLT 370 HRFMVWNSIG 380 IIRCYNDEQD 390 NAIDVEFHDT 400 SIHHATHLSN 410 TLNYTVADLS 420 HEAILLACES 430 TDELASKLHC 440 LHFSSWDSSK 450 EWIVDMPPNE 460 DIEAVCLGQG 470 WAAAATSSLL 480 LRLFTIGGVQ 490 KEVFSLPGPV 500 VSMAGHGEQL 510 IIVYHRGTGF 520 DGDQCLGIQL 530 LQLGKKKKQI 540 LHGDPLPLTR 550 KSYLVWLGFS 560 AEGTPCYVDS 570 EGIVRMLNRG 580 LGYTWTPICN 590 TREHCKGKSD 600 HYWVVGIHEN 610 PQHLRCIPCK 620 GSRFPPTLPR 630 PAIAVLSFKL 640 PYCQTGTEKG 650 QMEEQYWRSV 660 LFHNHLDYLA 670 KSGYEYEEST 680 KNQAIKEQQE 690 LLMKMLALSC 700 KLEREFRCVE 710 LADLMTQNAV 720 NLAIKYASRS 730 RRLILAQKLS 740 ELAVEKAAEL 750 AAPQAEEEEE 760 EEEDFRKKLN 770 AGYSNTPTEW 780 SQPRLRNRVE 790 EDTEDTEEVD 800 DIEEKPEIHK 810 HRQNPFFKSA 820 DSTDVPAIKS 830 GAVTSSSQGR 840 INPFKVSGSS 850 KEPANSFSSV 860 RSTNILDNMN 870 KSKKSALNRA 880 TNNEKSPVIK 890 PLVPKPKSKQ 900 ASAASFFQKR 910 TSQTDKTEEI 920 KEENTKNSSS 930 ETPAVCPQNT 940 ENQRPKTGFQ 950 MWLEENRSNI 960 LSDNPDFSDE 970 ADIIKEGMVR 980 FRVLSAEERK 990 AWAAKAKGGI 1000 ASDGAEEKKR 1010 KRVVDESHET 1020 ENQEEKTKEN 1030 LNLPKKQKPL 1040 NLSANQKLSA FAFKQE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0003677 DNA binding
Biological Process GO:0006261 DNA-templated DNA replication

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.