Search Results
Overview
| Uniprot ID | I3L9N5 |
|---|---|
| Protein Name | 26S proteasome non-ATPase regulatory subunit 5 |
| Gene Name | PSMD5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 315 | EGKQVLQKTGTRFER |
| 339 | KNASTELKIRCLDAV |
| 66 | VHVARNLKVDLQRGL |
| 81 | THTNDSVKILTLSQV |
Function
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5
Protein Sequence
10
MAAQVLALLR
20
EVSRLEAPLE
30
ELRALHLGPL
40
FSLLNENHRE
50
QTTLCVSILE
60
RLLQALEPVH
70
VARNLKVDLQ
80
RGLTHTNDSV
90
KILTLSQVGR
100
IVDNSDAVTE
110
ILNNAELLKQ
120
IVYCIGGENL
130
SVAKAAIKSL
140
SRISLTQAGL
150
EALFESNLLD
160
DLKSVMKTND
170
IVRYRVYELI
180
VEISSVSPES
190
LNYCTTSGLV
200
TQLLRELTGE
210
DVLVRATCIE
220
MVTSLAYTHH
230
GRQYLAQEGV
240
IDQISNIIVG
250
ADSDPFSSFY
260
LPGFVKFFGN
270
LAIMDSPQQI
280
CERYPVFVEK
290
VFEMTESQDP
300
TMIGVAVDTI
310
GILGSNVEGK
320
QVLQKTGTRF
330
ERLLMKIGYQ
340
AKNASTELKI
350
RCLDAVSSLF
360
YLPPEQQTDD
370
LLRMTESWFS
380
SLSRDPLELF
390
RGISNQPFPE
400
LHCAALKVFT
410
AIANQPWAQK
420
LMFNSPGFVE
430
YVMDRSVEHD
440
KASKDAKYEL
450
VKALANSKTI
460
AEIFGNPNYL
470
RLRTYLSEGP
480
YYVKPISTTA
VEGAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0043248 | proteasome assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.