Search Results
Overview
| Uniprot ID | I3L9W8 |
|---|---|
| Protein Name | Zinc phosphodiesterase ELAC protein 2 |
| Gene Name | ELAC2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 418 | VRGQCLLKYQLRPRR |
Function
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly
Protein Sequence
10
MWALRSLLGL
20
RSVAGRTMSQ
30
GPARRQRPPK
40
DPLRHLRTRE
50
KRGPSWAPGG
60
PNTVYVQVVA
70
AGGRDAGAAL
80
YVFSEYNRYL
90
FNCGEGVQRL
100
MQEHKLKVSR
110
LDNIFLTRMH
120
WANVGGLCGM
130
ILTLKETGLP
140
KCVLSGPPQL
150
EKYLDAIKTF
160
SGPLKGIDLA
170
VRPHSAPEYK
180
DETMTVSQVP
190
ICREGEQAAG
200
TPQPASSPER
210
PRAQPAADPG
220
SAEGEQRPAE
230
GVGQNTHGRD
240
PSLVVAFICK
250
LHLKKGNFLV
260
LKAKELGLPV
270
GTAAIAPIIA
280
AVKDGKSVTY
290
EGREILPEEI
300
CTPPDPGVAF
310
VVVECPDEGF
320
IQPVCENATF
330
RSYQGNAEAP
340
VALVVHMAPE
350
SVLLDSRYQQ
360
WMERFGPDTQ
370
HLVLNEHCES
380
VHNLRSHKIQ
390
TQLNLIHSGI
400
FPPLASLRPQ
410
EGGATFQVPT
420
VRGQCLLKYQ
430
LRPRREWQSS
440
DTTLLLDCGE
450
GTFGQLCRHY
460
GDDVDRVLGA
470
LAAVFVSHLH
480
ADHHTGLLNI
490
LLQRERALAS
500
LGRPLRPLLV
510
VAPTQLRTWL
520
QQYHNHCQQV
530
LQHVSVIPAK
540
CLQQGAEVSN
550
PDIERLISLL
560
LETCGLKEFQ
570
TCLVRHCKHA
580
FGCALVHPSG
590
WKLVYSGDTM
600
PCEALVQMGK
610
DATLLIHEAT
620
LEDGLEEEAV
630
EKTHSTTSQA
640
IGVGMRMHAE
650
FVLLNHFSQR
660
YAKIPLFSPD
670
FTEKVGIAFD
680
HMKVSLGDLP
690
TVPKLMAPLK
700
ALFAGDLEEM
710
EERREKRELR
720
QVRAALLAEV
730
GDGEPPQKRA
740
HAERPPSPQS
KKVRAQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0042645 | mitochondrial nucleoid |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0042781 | 3'-tRNA processing endoribonuclease activity |
| Molecular Function | GO:0046872 | metal ion binding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.