Search Results

Overview

Uniprot IDI3LB28
Protein NameNeuropilin
Gene NameNRP2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
233 IGKYCGTKTPSELRS

Function

High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF

Protein Sequence

10 MDMFPLTWIF 20 LALYFSGLQV 30 TGQPDPPCGG 40 RLNSKDAGYI 50 TSPGYPQDYP 60 SHQNCEWIVY 70 APEPNQKIVL 80 NFNPHFEIEK 90 HDCKYDFIEI 100 RDGDSESADL 110 LGKHCGNIAP 120 PTIISSGSVL 130 YIKFTSDYAR 140 QGAGFSLRYE 150 IFKTGSEDCS 160 KNFTSPNGTI 170 ESPGFPEKYP 180 HNLDCTFTIL 190 AKPKMEIILQ 200 FLTFDLEHDP 210 LQVGEGDCKY 220 DWLDIWDGIP 230 HVGPLIGKYC 240 GTKTPSELRS 250 ATGILSLTFH 260 TDMAVAKDGF 270 SARYYLVPQE 280 PQDNFQCNVP 290 LGMESGRIAN 300 EQISASSSYS 310 DGRWTPQQSR 320 LHGDDNGWTP 330 NLDSSKEYLQ 340 VDLRFLTVLT 350 AIATQGAISR 360 ETQNGYYVKS 370 YKLEVSTNGE 380 DWMVYRHGKN 390 HKVFQANNDA 400 SEVVLNKLHA 410 PLLTRFVRVR 420 PQTWHAGIAL 430 RLELFGCRVT 440 DAPCSNMLGM 450 LSGLIADSQI 460 SASSTREYLW 470 SPSAARLVSS 480 RSGWFPRIPQ 490 AQPGEEWLQV 500 DLGAPKTVKG 510 VIIQGARGGD 520 SITAVEARAF 530 VRKFKVAYSL 540 NGKDWEHIQD 550 PRTQQPKLFE 560 GNMHYDTPDI 570 RRFDPVPAQY 580 VRVYPERWSP 590 AGIGMRLEVL 600 GCDWTDSKPT 610 VETLGPTVKS 620 EETTTPYPID 630 EEATECGENC 640 SFEDDKDLQL 650 PSGFNCNFDF 660 PEEPCGWVYD 670 HAKWLRSTWT 680 SSSSPSDRTF 690 PDDRNFLRLQ 700 SDGRREGQYA 710 RLISPPVHLP 720 RSPVCMEFQY 730 QATGGRGVAL 740 QVVREASQES 750 KLLWVIREDQ 760 GSEWKHGRII 770 LPSYDMEYQI 780 VFEGVIGKGR 790 SGEIAIDDIR 800 ISTDVPLENC 810 MEPISAFADE 820 YEVVDWSNSS 830 SPTSGSGAPL 840 ADKEKSWLYT 850 LDPILITIIA 860 MSSLGVLLGA 870 TCAGLLLYCT 880 CSYSGLSSRS 890 CTTLENYNFE 900 LYDGLKHKVK 910 MNHQKCCSEA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030424 axon
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0045211 postsynaptic membrane
Molecular Function GO:0008201 heparin binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0017154 semaphorin receptor activity
Molecular Function GO:0005021 vascular endothelial growth factor receptor activity
Biological Process GO:0001525 angiogenesis
Biological Process GO:0048846 axon extension involved in axon guidance
Biological Process GO:0007411 axon guidance
Biological Process GO:1904835 dorsal root ganglion morphogenesis
Biological Process GO:0021612 facial nerve structural organization
Biological Process GO:1903375 facioacoustic ganglion development
Biological Process GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus
Biological Process GO:1901166 neural crest cell migration involved in autonomic nervous system development
Biological Process GO:0003148 outflow tract septum morphogenesis
Biological Process GO:0099175 regulation of postsynapse organization
Biological Process GO:0097374 sensory neuron axon guidance
Biological Process GO:0061549 sympathetic ganglion development
Biological Process GO:0097490 sympathetic neuron projection extension
Biological Process GO:0097491 sympathetic neuron projection guidance
Biological Process GO:0061551 trigeminal ganglion development
Biological Process GO:0036486 ventral trunk neural crest cell migration
Biological Process GO:0021649 vestibulocochlear nerve structural organization

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.