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Overview

Uniprot IDI3LBH0
Protein NameReticulon
Gene NameRTN1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
82 SVLQAVQKTDEGHPF

Function

Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity

Protein Sequence

10 MQATADSTKM 20 DCVWSNWKSQ 30 AIDLLYWRDI 40 KQTGIVFGSF 50 LLLLFSLTQF 60 SVVSVVAYLA 70 LAALSATISF 80 RIYKSVLQAV 90 QKTDEGHPFK 100 AYLELEITLS 110 QEQIQKYTDC 120 LQFYVNSTLK 130 ELRRLFLVQD 140 LVDSLKFAVL 150 MWLLTYVGAL 160 FNGLTLLLMA 170 VVSMFTLPVV 180 YVKHQAQIDQ 190 YLGLVRTHIN 200 AVVAKIQAKI PGAKRHAE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.