Search Results

Overview

Uniprot ID	I3LCA1
Protein Name	ATP-dependent 6-phosphofructokinase
Gene Name	PFKM
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
693	FDRNFATKMGAKAMN

Function

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis

Protein Sequence

10 MHKEEVHLKF 20 FMCVIQSRQL 30 VRTPQRTEWI 40 MTHEEHHAAK 50 SLGVGKAIAV 60 LTSGGDAQGM 70 NAAVRAVVRV 80 GIYTGARVFF 90 VHEGYQGLVD 100 GGDNIREATW 110 ESVSMMLQLG 120 GTVIGSARCK 130 DFREREGRLR 140 AAHNLVKRGI 150 TNLCVIGGDG 160 SLTGADTFRS 170 EWGDLLNDLQ 180 KAGKITAEEA 190 NKSSYLNIVG 200 LVGSIDNDFC 210 GTDMTIGTDS 220 ALHRIIEIVD 230 AITTTAQRYL 240 ALVTSLSCGA 250 DWVFIPECPP 260 DDAWEEHLCR 270 RLSETRTRGS 280 RLNIIIVAEG 290 AIDKNGQPIT 300 SENIKDLVVK 310 RLGYDTRVTV 320 LGHVQRGGTP 330 SAFDRILGSR 340 MGVEAVMALL 350 EGTPDTPACV 360 VSLSGNQAVR 370 LPLMECVQVT 380 KDVTKAMNEK 390 RFDEAMKLRG 400 RSFMNNWEVY 410 KLLAHVRPPV 420 TKSGSYTVAV 430 MNVGAPAAGM 440 NAAVRSTVRI 450 GLIQGNRVLV 460 VHDGFEGLAK 470 GQIEEAGWSY 480 VGGWTGQGGS 490 KLGTKRTLPK 500 KSFEQISANI 510 TKFNIQGLVI 520 IGGFEAYTGG 530 LELMEGRKQY 540 DELCIPFVVI 550 PATVSNNVPG 560 SDFSVGADTA 570 LNTICMTCDR 580 IKQSAAGTKR 590 RVFIIETMGG 600 YCGYLATMAG 610 LAAGADAAYI 620 FEEPFTIRDL 630 QVNVEHLVQK 640 MKTTVKRGLV 650 LRNEKCNENY 660 TTDFIFNLYS 670 EEGKGIFDSR 680 KNVLGHMQQG 690 GSPTPFDRNF 700 ATKMGAKAMN 710 WMSGKIKESY 720 RNGRIFANTP 730 DSGCVLGMRK 740 RALVFQPVTE 750 LKEQTDFEHR 760 IPKEQWWLKL 770 RPILKILAKY 780 EIDLDTSEHA 790 HLEHITRKRS GEATI

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Molecular Function	GO:0003872	6-phosphofructokinase activity
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0046872	metal ion binding
Biological Process	GO:0006002	fructose 6-phosphate metabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.