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Overview

Uniprot IDI3LEY2
Protein NameAnnexin
Gene NameANXA7
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
268 WSLRNAMKGAGTQER
306 EFGRDLEKDIRSDTS

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis

Protein Sequence

10 MSYPGYTPTG 20 YPPFPGYPPA 30 GQESSFPPPG 40 QYPYPSGFPP 50 MGGGAYPPAP 60 SSGYPGAGGY 70 PAPGGYPAPG 80 GYPGAPQPGG 90 APSYPGVLPG 100 QGFGAPPGGA 110 GFSGYPQPPS 120 QSYGGGPAQV 130 PVPGGFPGGP 140 MPSQYPGGQT 150 PYPSQISTES 160 FPSYPVFSPI 170 SLDYSSELAT 180 VAQGTIRPAA 190 NFDAMRDAEI 200 LRKAMKGFGT 210 DEQAIIDVVA 220 NRSNDQRQKI 230 KAAFKTMYGK 240 DLIKDLKSEL 250 SGNMEELILA 260 LFMPSTYYDA 270 WSLRNAMKGA 280 GTQERVLIEI 290 LCTRTNQEIR 300 EIVRCYQSEF 310 GRDLEKDIRS 320 DTSGHFERLL 330 VSMCQGNRDE 340 NQNVNPQMAQ 350 EDAQRLYQAG 360 EGRLGTDESC 370 FNMILATRSF 380 PQLKATMEAY 390 SRMANRDLLS 400 SVGREFSGNV 410 ESGLKTILQC 420 ALNRPAFFAE 430 RLYYSMKGAG 440 TDDSTLVRIV 450 VTRSEIDLVQ 460 IKQMFSQMYQ 470 KTLGTMIASD 480 TSGDYRRLLL AIVGQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0042584 chromaffin granule membrane
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0012506 vesicle membrane
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0005544 calcium-dependent phospholipid binding
Molecular Function GO:0048306 calcium-dependent protein binding
Molecular Function GO:0005178 integrin binding
Molecular Function GO:0001786 phosphatidylserine binding
Biological Process GO:0006914 autophagy
Biological Process GO:0030855 epithelial cell differentiation
Biological Process GO:0010629 negative regulation of gene expression

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.