Search Results
Overview
| Uniprot ID | I3LG77 |
|---|---|
| Protein Name | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
| Gene Name | SAMHD1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 288 | KNATWPYKGRPKEKS |
| 346 | RVCEVDNKKHICTRE |
| 354 | KHICTREKEVGNLYD |
| 529 | YCKSDPNKAIIITKN |
| 561 | YCKKTDEKSLFAARQ |
Function
No function data available.
Protein Sequence
10
MQSADSQQPS
20
KRPRCDGSPT
30
TPPNTPPAAA
40
ERSLGPNLHP
50
DHRTWGPEQV
60
CGFLNRSGFG
70
DSELLERCRE
80
KKITGSILPF
90
LDESLLEDLG
100
VSSYEKRMKL
110
LNYIQRLGQT
120
HVDTVKVIND
130
PIHGHIELHP
140
LLIRIIDTPQ
150
FQRLRYIKQL
160
GGGYYVFPGA
170
SHNRFEHSLG
180
VGYLAGCLVR
190
ELSEKQPELQ
200
ISERDMLCVQ
210
IAGLCHDLGH
220
GPFSHMFDGR
230
FIPLARPDVK
240
WTHEQGSVNM
250
FEHLVNSNGL
260
IDVMEHYGLI
270
PEEDIWFIKE
280
QITGPLESPV
290
KNATWPYKGR
300
PKEKSFLYEI
310
VANKRNGIDV
320
DKWDYFARDC
330
HHLGIQNNFD
340
YKRFIKFARV
350
CEVDNKKHIC
360
TREKEVGNLY
370
DMFHTRNCLH
380
RRAYQHKVGN
390
IIDTMITDAF
400
LKADPYIEIT
410
GSEGKKYRIS
420
TAIDDMEAFT
430
KLTDNIFLEI
440
LYSTDPKLDA
450
ARAILKKIEC
460
RNLYKFVGET
470
QPGRQDKIKR
480
ENYESLPKGV
490
ASAKPSNIQL
500
EAELKAEDFI
510
VDVINMDYGM
520
EDKNPIDNVR
530
FYCKSDPNKA
540
IIITKNQVSQ
550
LLPERFAEQL
560
IRVYCKKTDE
570
KSLFAARQHF
580
VQWCLDNDFT
590
KPQDGDVVAP
600
LITPRKLEWN
610
STHSAQSQAR
620
TREASKSRVR
LFAKDSV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0035861 | site of double-strand break |
| Cellular Component | GO:0097197 | tetraspanin-enriched microdomain |
| Molecular Function | GO:0106375 | deoxynucleoside triphosphate hydrolase activity |
| Molecular Function | GO:0032567 | dGTP binding |
| Molecular Function | GO:0008832 | dGTPase activity |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0004540 | RNA nuclease activity |
| Molecular Function | GO:0003697 | single-stranded DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0046061 | dATP catabolic process |
| Biological Process | GO:0051607 | defense response to virus |
| Biological Process | GO:0006203 | dGTP catabolic process |
| Biological Process | GO:0110025 | DNA strand resection involved in replication fork processing |
| Biological Process | GO:0000724 | double-strand break repair via homologous recombination |
| Biological Process | GO:0045087 | innate immune response |
| Biological Process | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway |
| Biological Process | GO:0051289 | protein homotetramerization |
| Biological Process | GO:0045088 | regulation of innate immune response |
| Biological Process | GO:0016446 | somatic hypermutation of immunoglobulin genes |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.