Search Results

Overview

Uniprot IDI3LGP4
Protein NameDNA-directed RNA polymerase subunit beta
Gene NamePOLR2B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1060 RIPQIGDKFASRHGQ
1269 ECRGCRNKTQISLVR
547 EVRIYAQKFIDRGKD

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

Protein Sequence

10 MKPLRPENPP 20 KAELKGLLFV 30 QQHCKTRLHS 40 VAVTRPRGAA 50 TEESTPKLRM 60 CSTNLSQALA 70 YFRAGANLTA 80 ASLWAGFRGS 90 RRIFWERRKR 100 KSLCLALRPG 110 GACWRWLLAV 120 SCVSLRGLGA 130 PGSCANMYDA 140 DEDMQYDEDD 150 DEITPDLWQE 160 ACWIVISSYF 170 DEKGLVRQQL 180 DSFDEFIQMS 190 VQRIVEDAPP 200 IDLQAEAQHA 210 SGEVEEPPRY 220 LLKFEQIYLS 230 KPTHWERDGA 240 PSPMMPNEAR 250 LRNLTYSAPL 260 YVDITKTVIK 270 EGEEQLQTQH 280 QKTFIGKIPI 290 MLRSTYCLLN 300 GLTDRDLCEL 310 NECPLDPGGY 320 FIINGSEKVL 330 IAQEKMATNT 340 VYVFAKKDSK 350 YAYTGECRSC 360 LENSSRPTST 370 IWVSMLARGG 380 QGAKKSAIGQ 390 RIVATLPYIK 400 QEVPIIIVFR 410 ALGFVSDRDI 420 LEHIIYDFED 430 PEMMEMVKPS 440 LDEAFVIQEQ 450 NVALNFIGSR 460 GAKPGVTKEK 470 RIKYAKEVLQ 480 KEMLPHVGVS 490 DFCETKKAYF 500 LGYMVHRLLL 510 AALGRRELDD 520 RDHYGNKRLD 530 LAGPLLAFLF 540 RGMFKNLLKE 550 VRIYAQKFID 560 RGKDFNLELA 570 IKTRIISDGL 580 KYSLATGNWG 590 DQKKAHQARA 600 GVSQVLNRLT 610 FASTLSHLRR 620 LNSPIGRDGK 630 LAKPRQLHNT 640 LWGMVCPAET 650 PEGHAVGLVK 660 NLALMAYISV 670 GSQPSPILEF 680 LEEWSMENLE 690 EISPAAIADA 700 TKIFVNGCWV 710 GIHKDPEQLM 720 NTLRKLRRQM 730 DIIVSEVSMI 740 RDIREREIRI 750 YTDAGRICRP 760 LLIVEKQKLL 770 LKKRHIDQLK 780 EREYNNYSWQ 790 DLVASGVVEY 800 IDTLEEETVM 810 LAMTPDDLQE 820 KEVAYCSTYT 830 HCEIHPSMIL 840 GVCASIIPFP 850 DHNQSPRNTY 860 QSAMGKQAMG 870 VYITNFHVRM 880 DTLAHVLYYP 890 QKPLVTTRSM 900 EYLRFRELPA 910 GINSIVAIAS 920 YTGYNQEDSV 930 IMNRSAVDRG 940 FFRSVFYRSY 950 KEQESKKGFD 960 QEEVFEKPTR 970 ETCQGMRHAI 980 YDKLDDDGLI 990 APGVRVSGDD 1000 VIIGKTVTLP 1010 ENEDELEGTN 1020 RRYTKRDCST 1030 FLRTSETGIV 1040 DQVMVTLNQE 1050 GYKFCKIRVR 1060 SVRIPQIGDK 1070 FASRHGQKGT 1080 CGIQYRQEDM 1090 PFTCEGITPD 1100 IIINPHAIPS 1110 RMTIGHLIEC 1120 LQGKVSANKG 1130 EIGDATPFND 1140 AVNVQKISNL 1150 LSDYGYHLRG 1160 NEVLYNGFTG 1170 RKITSQIFIG 1180 PTYYQRLKHM 1190 VDDKIHSRAR 1200 GPIQILNRQP 1210 MEGRSRDGGL 1220 RFGEMERDCQ 1230 IAHGAAQFLR 1240 ERLFEASDPY 1250 QVHVCNLCGI 1260 MAIANTRTHT 1270 YECRGCRNKT 1280 QISLVRMPYA 1290 CKLLFQELMS 1300 MSIAPRMMSV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000781 chromosome, telomeric region
Cellular Component GO:0005665 RNA polymerase II, core complex
Molecular Function GO:0003682 chromatin binding
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0003899 DNA-directed RNA polymerase activity
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0032549 ribonucleoside binding
Molecular Function GO:0003968 RNA-directed RNA polymerase activity
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006354 DNA-templated transcription elongation
Biological Process GO:0006368 transcription elongation by RNA polymerase II
Biological Process GO:0006367 transcription initiation at RNA polymerase II promoter

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.