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Overview

Uniprot IDI3LHK5
Protein NameActin-related protein 10
Gene NameACTR10
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
225 SDLTRGLKIQAAKFN
375 LGSRSVSKEYYNQTG
44 CIIPSVIKKAGMPKP

Function

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules

Protein Sequence

10 MPLYEGLGSG 20 GEKTAVVIDL 30 GEAFTKCGFA 40 GETGPRCIIP 50 SVIKKAGMPK 60 PIKVVQYNIN 70 TEELYSYLKE 80 FIHILYFRHL 90 LVNPRDRRVV 100 VIESVLCPSH 110 FRETLTRVLF 120 KYFEVPSVLL 130 APSHLMALLT 140 LGINSAMVLD 150 CGYRESLVLP 160 IYEGIPVLNC 170 WGALPLGGKA 180 LHKELETQLL 190 EQCTVDTGAA 200 KEQSLPSVMG 210 SIPEGVLEDI 220 KVRTCFVSDL 230 TRGLKIQAAK 240 FNIDGNTERP 250 SPPPNVDYPL 260 DGEKILHVLG 270 SIRDSVVEIL 280 FEQDNEEKSV 290 ATLILDSLMQ 300 CPIDTRKQLA 310 ENLVIIGGTS 320 MLPGFLHRLL 330 AEIRYLVEKP 340 KYKKTLGTKT 350 FRIHTPPAKA 360 NCVAWLGGAI 370 FGALQDILGS 380 RSVSKEYYNQ 390 TGRIPDWCSL 400 NNPPLEMVFD 410 VGKSQPPLMK RAFSTEK

Gene Ontology

Classification GO ID Description
Cellular Component GO:1904115 axon cytoplasm
Cellular Component GO:0005869 dynactin complex
Cellular Component GO:0005634 nucleus
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:0007017 microtubule-based process
Biological Process GO:0098958 retrograde axonal transport of mitochondrion

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.