Search Results
Overview
| Uniprot ID | I3LII4 |
|---|---|
| Protein Name | Serine/threonine-protein kinase PLK |
| Gene Name | PLK1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 61 | LRGRFLGKGGFAKCF |
Function
No function data available.
Protein Sequence
10
MSAAATTGKL
20
ARAPADPGKA
30
GGPGVAAPGA
40
PAAAPPAKEI
50
PEVLVDPRSR
60
RRYLRGRFLG
70
KGGFAKCFEI
80
SDADTKEVFA
90
GKIVPKSLLL
100
KPHQKEKMSM
110
EISIHRSLAH
120
QHVVGFHGFF
130
EDNDFVFVVL
140
ELCRRRSLLE
150
LHKRRKALTE
160
PEARYYLRQI
170
VLGCQYLHRN
180
RVIHRDLKLG
190
NLFLNEDLEV
200
KIGDFGLATK
210
VEYDGERKKT
220
LCGTPNYIAP
230
EVLSKKGHSF
240
EVDVWSIGCI
250
MYTLLVGKPP
260
FETSCLKETY
270
LRIKKNEYSI
280
PKHINPVAAS
290
LIQKMLQTDP
300
TARPTIHELL
310
NDEFFTSGYI
320
PARLPITCLT
330
IPPRFSIAPS
340
SLDPSSRKPL
350
TVLNKGMENP
360
MPERPREKEE
370
PVVRETSEAA
380
DGHLGDMLQQ
390
LHSVNASKPS
400
ERGLVRQEEE
410
DPACIPIFWV
420
SKWVDYSDKY
430
GLGYQLCDNS
440
VGVLFNDSTR
450
LILYNDGDSL
460
QYIERDGTES
470
YLTVSSHPNS
480
LIKKITLLKY
490
FRNYMSEHLL
500
KAGANITPRE
510
GDELARLPYL
520
RTWFRTRSAI
530
ILHLSNGCVQ
540
INFFQDHTKL
550
ILCPLMAAVT
560
YIDEKRDFRT
570
YRLSLLEEFG
580
CSKELASRLR
590
YARTMVDKLL
600
SSRSATNRLK
ASS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0034451 | centriolar satellite |
| Cellular Component | GO:0005814 | centriole |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0097431 | mitotic spindle pole |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000940 | outer kinetochore |
| Cellular Component | GO:0005876 | spindle microtubule |
| Cellular Component | GO:0051233 | spindle midzone |
| Cellular Component | GO:0000922 | spindle pole |
| Cellular Component | GO:0000795 | synaptonemal complex |
| Molecular Function | GO:0010997 | anaphase-promoting complex binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0106310 | protein serine kinase activity |
| Molecular Function | GO:0004674 | protein serine/threonine kinase activity |
| Biological Process | GO:0030953 | astral microtubule organization |
| Biological Process | GO:0007098 | centrosome cycle |
| Biological Process | GO:0097681 | double-strand break repair via alternative nonhomologous end joining |
| Biological Process | GO:0000086 | G2/M transition of mitotic cell cycle |
| Biological Process | GO:0001578 | microtubule bundle formation |
| Biological Process | GO:1903673 | mitotic cleavage furrow formation |
| Biological Process | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
| Biological Process | GO:0000070 | mitotic sister chromatid segregation |
| Biological Process | GO:0007094 | mitotic spindle assembly checkpoint signaling |
| Biological Process | GO:0007052 | mitotic spindle organization |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:2000042 | negative regulation of double-strand break repair via homologous recombination |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0045842 | positive regulation of mitotic metaphase/anaphase transition |
| Biological Process | GO:1905559 | positive regulation of mitotic nuclear envelope disassembly |
| Biological Process | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0071168 | protein localization to chromatin |
| Biological Process | GO:0032465 | regulation of cytokinesis |
| Biological Process | GO:1901673 | regulation of mitotic spindle assembly |
| Biological Process | GO:1904776 | regulation of protein localization to cell cortex |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.