Search Results
Overview
| Uniprot ID | I3LIN2 |
|---|---|
| Protein Name | Synapse-associated protein 1 |
| Gene Name | SYAP1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 135 | MRFALVPKLVKEEVF |
| 198 | KTPPVVIKSQLKTQE |
Function
Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation
Protein Sequence
10
MFRGLSSWFG
20
LEQPAPGGRQ
30
SEGDGQPKGD
40
APPEQRSEAV
50
AETAEGEPQQ
60
AGDQELLHQA
70
KGLGKAAVPP
80
WVDSNDEETI
90
QQQVLALSAD
100
KRNFLRDPPA
110
GVQFNFDFDQ
120
MYPVALVMLQ
130
EDELLSRMRF
140
ALVPKLVKEE
150
VFWRNYFYRV
160
SLIKQSAQLT
170
ALAAQQQAAG
180
KEEKSRGRED
190
ESPLTEAVRP
200
KTPPVVIKSQ
210
LKTQEDEEEI
220
STSPGVSEFV
230
SDAFDACNLD
240
QEDLRKEMEQ
250
LVLDKKEQET
260
VVLEEDSADW
270
EKELQQELQE
280
YEVVTESEKR
290
DENWDKEIEK
MLQEEN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:0032869 | cellular response to insulin stimulus |
| Biological Process | GO:0045600 | positive regulation of fat cell differentiation |
| Biological Process | GO:0038203 | TORC2 signaling |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.