Search Results
Overview
| Uniprot ID | I3LIN5 |
|---|---|
| Protein Name | Ubiquitin carboxyl-terminal hydrolase |
| Gene Name | USP14 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 267 | SEEEEVTKGKENQLQ |
| 291 | KYLFTGLKLRLQEEI |
| 313 | QRNALYIKSSKISRL |
| 342 | EKESVNAKVLKDVKF |
| 387 | KKVNQQPKASDKKSS |
| 441 | GHYVSWVKRKQDEWI |
| 62 | DDDWGNIKIKNGMTL |
Function
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes
Protein Sequence
10
MPLYSVTVKW
20
GKEKFEGVEL
30
NTDEPPMVFK
40
AQLFALTGVQ
50
PARQKVMVKG
60
GTLKDDDWGN
70
IKIKNGMTLL
80
MMGSADALPE
90
EPSAKTVFVE
100
DMTEEQLASA
110
MELPCGLTNL
120
GNTCYMNATV
130
QCIRSVPELK
140
DALKRYAGAL
150
RASGEMASAQ
160
YITAALRDLF
170
DSMDKTSSSI
180
PPIILLQFLH
190
MAFPQFAEKG
200
EQGQYLQQDA
210
NECWIQMMRV
220
LQQKLEAIED
230
DTVKETDSSS
240
ASAVTPSKKK
250
SLIDQFFGVE
260
FETTMKCTES
270
EEEEVTKGKE
280
NQLQLSCFIN
290
QEVKYLFTGL
300
KLRLQEEITK
310
QSPTLQRNAL
320
YIKSSKISRL
330
PAYLTIQMVR
340
FFYKEKESVN
350
AKVLKDVKFP
360
LMLDVYELCT
370
PELQEKMVSF
380
RSKFKDLEDK
390
KVNQQPKASD
400
KKSSPQKEVK
410
YEPFSFADDI
420
GSNNCGYYDL
430
QAVLTHQGRS
440
SSSGHYVSWV
450
KRKQDEWIKF
460
DDDKVSIVTP
470
EDILRLSGGG
480
DWHIAYVLLY
490
GPRRVEIMEE
ESE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000502 | proteasome complex |
| Molecular Function | GO:0004843 | cysteine-type deubiquitinase activity |
| Molecular Function | GO:0070628 | proteasome binding |
| Biological Process | GO:1904293 | negative regulation of ERAD pathway |
| Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0016579 | protein deubiquitination |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.