Search Results

Overview

Uniprot IDI3LJ73
Protein NameGMP synthase [glutamine-hydrolyzing]
Gene NameGMPS
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
165 THGDSVDKVADGFKV
171 DKVADGFKVVARSGN
294 QSVEEALKKLGIQVK
344 TSPEEKRKIIGDTFV
395 SGKAELIKTHHNDTE
418 GKVIEPLKDFHKDEV
493 HTLLQRVKACTTEED
633 FDRDPLQKQPSCQRS

Function

Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate

Protein Sequence

10 MALESSTIHF 20 SPQKKLENAG 30 GDLKDGHHHY 40 EGAVVILDAG 50 AQYGKVIDRR 60 VRELFVQSEI 70 FPLETPAFAI 80 KEQGFRAIII 90 SGGPNSVYAE 100 DAPWFDPAIF 110 TIGKPVLGIC 120 YGMQMMNKVF 130 GGTVHKKSVR 140 EDGVFSISVD 150 NTCSLFRGLQ 160 KEEIVLLTHG 170 DSVDKVADGF 180 KVVARSGNIV 190 AGIANESKKL 200 YGVQFHPEVG 210 LTENGKVILK 220 NFLYDIAGCS 230 GTFTVQNREL 240 ECIREIKERV 250 GTSKVLVLLS 260 GGVDSTVCTA 270 LLNRALNQDQ 280 VIAVHIDNGF 290 MRKRESQSVE 300 EALKKLGIQV 310 KVINAAHSFY 320 NGTTTLPISD 330 EDRTPRKRIS 340 KTLNMTTSPE 350 EKRKIIGDTF 360 VKIANEVIGE 370 MNLKPEEVFL 380 AQGTLRPDLI 390 ESASLVASGK 400 AELIKTHHND 410 TELIRKLREE 420 GKVIEPLKDF 430 HKDEVRILGR 440 ELGLPEELVS 450 RHPFPGPGLA 460 IRVICAEEPY 470 ICKDFPETNN 480 ILKIVADFSA 490 SVKKPHTLLQ 500 RVKACTTEED 510 QEKLMQITSL 520 HSLNAFLLPI 530 KTVGVQGDCR 540 SYSYVCGISS 550 KDEPDWESLI 560 FLARLIPRMC 570 HNINRVVYIF 580 GPPVKEPPTD 590 VTPTFLTTGV 600 LSTLRQADFE 610 AHNILRESGY 620 AGKISQMPVI 630 LTPLHFDRDP 640 LQKQPSCQRS 650 VVIRTFITSD 660 FMTGIPATPG 670 NEIPVEVVLK 680 MVTEIKKIPG 690 ISRIMYDLTS KPPGTTEWE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0003921 GMP synthase activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.