Search Results
Overview
| Uniprot ID | I3LJD8 |
|---|---|
| Protein Name | 5'-AMP-activated protein kinase catalytic subunit alpha-1 |
| Gene Name | PRKAA1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 125 | KNGRLDEKESRRLFQ |
| 56 | TGHKVAVKILNRQKI |
| 80 | RREIQNLKLFRHPHI |
Function
No function data available.
Protein Sequence
10
MRRLSSWRKM
20
ATAEKQKHDG
30
RVKIGHYILG
40
DTLGVGTFGK
50
VKVGKHELTG
60
HKVAVKILNR
70
QKIRSLDVVG
80
KIRREIQNLK
90
LFRHPHIIKL
100
YQVISTPSDI
110
FMVMEYVSGG
120
ELFDYICKNG
130
RLDEKESRRL
140
FQQILSGVDY
150
CHRHMVVHRD
160
LKPENVLLDA
170
HMNAKIADFG
180
LSNMMSDGEF
190
LRTSCGSPNY
200
AAPEVISGRL
210
YAGPEVDIWS
220
SGVILYALLC
230
GTLPFDDDHV
240
PTLFKKICDG
250
IFYTPQYLNP
260
SVISLLKHML
270
QVDPMKRATI
280
KDIREHEWFK
290
QDLPKYLFPE
300
DPSYSSTMID
310
DEALKEVCEK
320
FECSEEEVLS
330
CLYNRNHQDP
340
LAVAYHLIID
350
NRRIMNEAKD
360
FYLATSPPDS
370
FLDDHHLTRP
380
HPERVPFLVA
390
ETPRARHTLD
400
ELNPQKSKHQ
410
GVRKAKWHLG
420
IRSQSRPNDI
430
MAEVCRAIKQ
440
LDYEWKVVNP
450
YYLRVRRKNP
460
VTSTYSKMSL
470
QLYQVDSRTY
480
LLDFRSIDDE
490
ITEAKSGTAT
500
PQRSGSVSNY
510
RACQRNDSDA
520
EAQGKSSEAS
530
LTSSVTSLDS
540
SPVDLTPRPG
550
SHTIEFFEMC
ANLIKILAQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0106310 | protein serine kinase activity |
| Molecular Function | GO:0004674 | protein serine/threonine kinase activity |
| Molecular Function | GO:0050321 | tau-protein kinase activity |
| Biological Process | GO:0006914 | autophagy |
| Biological Process | GO:0061762 | CAMKK-AMPK signaling cascade |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:0042149 | cellular response to glucose starvation |
| Biological Process | GO:0071333 | cellular response to glucose stimulus |
| Biological Process | GO:0034599 | cellular response to oxidative stress |
| Biological Process | GO:0006695 | cholesterol biosynthetic process |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0097009 | energy homeostasis |
| Biological Process | GO:0006633 | fatty acid biosynthetic process |
| Biological Process | GO:0035556 | intracellular signal transduction |
| Biological Process | GO:0061744 | motor behavior |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:1903944 | negative regulation of hepatocyte apoptotic process |
| Biological Process | GO:0050995 | negative regulation of lipid catabolic process |
| Biological Process | GO:1904262 | negative regulation of TORC1 signaling |
| Biological Process | GO:0070050 | neuron cellular homeostasis |
| Biological Process | GO:1904179 | positive regulation of adipose tissue development |
| Biological Process | GO:0010508 | positive regulation of autophagy |
| Biological Process | GO:1903109 | positive regulation of mitochondrial transcription |
| Biological Process | GO:1903829 | positive regulation of protein localization |
| Biological Process | GO:1903955 | positive regulation of protein targeting to mitochondrion |
| Biological Process | GO:0050870 | positive regulation of T cell activation |
| Biological Process | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell |
| Biological Process | GO:1990044 | protein localization to lipid droplet |
| Biological Process | GO:0072659 | protein localization to plasma membrane |
| Biological Process | GO:0042752 | regulation of circadian rhythm |
| Biological Process | GO:0070507 | regulation of microtubule cytoskeleton organization |
| Biological Process | GO:0062028 | regulation of stress granule assembly |
| Biological Process | GO:0043114 | regulation of vascular permeability |
| Biological Process | GO:0010332 | response to gamma radiation |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
| Biological Process | GO:0009411 | response to UV |
| Biological Process | GO:0048511 | rhythmic process |
| Biological Process | GO:0016055 | Wnt signaling pathway |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity |
| Molecular Function | GO:0004679 | AMP-activated protein kinase activity |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0140823 | histone H2BS36 kinase activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.