Search Results
Overview
| Uniprot ID | I3LJT9 |
|---|---|
| Protein Name | Protein phosphatase methylesterase 1 |
| Gene Name | PPME1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 269 | LLFLQTKKDHPYTWR |
| 30 | GGSQSGAKMRMGPGR |
Function
Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme
Protein Sequence
10
MSALEKSMHL
20
GRLPSRPPLP
30
GSGGSQSGAK
40
MRMGPGRKRD
50
FSPVPWSQYF
60
ESMEDVEVEN
70
ETGKDISFAE
80
WLSGSEGPVL
90
LLLHGGGHSA
100
LSWAVFTAAI
110
ISRVQCRIVA
120
LDLRGHGETV
130
PAFFPSLCRD
140
VGNVVEAMYG
150
DLPPPIILLG
160
LCMIDVVEGT
170
AMDALNSMQN
180
FLRGRPKTFK
190
SLENAIEWSV
200
KSGQIRNLES
210
ARVSMVGQVK
220
QCEGITSPEG
230
SKSIVEGIIE
240
EEEEDEEGSE
250
SVNKRKKEDD
260
MEGLPSETQH
270
LLLFLQTKKD
280
HPYTWRIELA
290
KTEKYWDGWF
300
RGLSNLFLSC
310
PIPKLLLLAG
320
VDRLDKDLTI
330
GQMQGKFQMQ
340
VLPQCGHAVH
350
EDAPDKVAEA
360
VATFLIRHRF
AEPIGGFQW
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0051723 | protein methylesterase activity |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.