Overview
| Uniprot ID | I3LQS7 |
|---|
| Protein Name | U3 small nucleolar RNA-interacting protein 2 |
|---|
| Gene Name | RRP9 |
|---|
| Organism | Sus scrofa |
|---|
Kla Sites from experimental identification
| Position |
Flanking peptide |
| 12 |
VAARKRGKSASGAGA |
| 129 |
RLQKSVAKEIQAPAP |
| 84 |
EKKLRLAKLYLEQLK |
Function
Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome
Protein Sequence
10
MSATVAARKR
20
GKSASGAGAG
30
AGAGKRRRKG
40
DSSGDKGKSK
50
GGGKMNEEIS
60
SDSENESIAP
70
RKTEEEEEEE
80
LEETAQEKKL
90
RLAKLYLEQL
100
KQQEEEKAEA
110
REFEEDQVAG
120
KLKEDVLEQR
130
GRLQKSVAKE
140
IQAPAPADIR
150
ILRGHQLSIT
160
CLVITPDDLA
170
IFSAAKDCTI
180
IKWSVESGRK
190
LHVIPRAKKG
200
AEGQPPGHSS
210
HILCMAISSD
220
GKYLASGDRS
230
KLILIWEAQS
240
CRHLYTFTGH
250
RDAVSGLAFR
260
RGTHQLYSTS
270
HDRSVKVWNV
280
AENSYVETLF
290
GHQDAVAALD
300
ALSRECCVTA
310
GGRDGTVRVW
320
KIPEESQLVF
330
YGHQGSIDSI
340
QLINEEHMVS
350
GADDGSVALW
360
GLSKKRPLAL
370
QREAHGLRGE
380
QGLEQPFWVS
390
SVAALLNTDL
400
IATGSHNNSV
410
RLWQCGEGFR
420
QLDLLCDIPL
430
VGFINSLKFS
440
SAGDFLVAGV
450
GQEHRLGRWW
460
RIKEARNSVC
470
IIPLHRAPRP
PAAGS
Gene Ontology
| Classification |
GO ID |
Description |
| Cellular Component |
GO:0031428 |
box C/D methylation guide snoRNP complex |
| Cellular Component |
GO:0032040 |
small-subunit processome |
| Molecular Function |
GO:0030515 |
snoRNA binding |
| Molecular Function |
GO:0034511 |
U3 snoRNA binding |
| Biological Process |
GO:0042274 |
ribosomal small subunit biogenesis |
| Biological Process |
GO:0006364 |
rRNA processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.