Search Results
Overview
| Uniprot ID | I3LT95 |
|---|---|
| Protein Name | Proteasome assembly chaperone 1 |
| Gene Name | PSMG1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 159 | KVFGSCPKKNMQVTV |
| 160 | VFGSCPKKNMQVTVL |
| 193 | TPFLRALKTQNFREA |
Function
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization
Protein Sequence
10
MAATFFGEVV
20
KAPCRAGTED
30
EEEEEEGRRE
40
TPEDREVRRQ
50
LARKREVRLL
60
RRQTKTSLDV
70
SLLEKYPCSK
80
FIIAIGNNAV
90
AFLSSFVMNS
100
GVWEEVGCAK
110
LWNEWCRTTD
120
TTHLSPAEAF
130
CVFYHLKSNP
140
SVLLCQCSCY
150
VAEDQQFQWL
160
EKVFGSCPKK
170
NMQVTVLTCR
180
HVTDFKTSES
190
TSSLHTPFLR
200
ALKTQNFREA
210
PCCSLLEQPN
220
IVHDLPAAVL
230
SYCQVWKIPA
240
VLYLCYTDVM
250
KLDLITVEAF
260
KPVLSSRSLK
270
GLVKNIPQST
280
EILKKLMTTN
EIQSNIYT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0000502 | proteasome complex |
| Cellular Component | GO:0101031 | protein folding chaperone complex |
| Molecular Function | GO:0060090 | molecular adaptor activity |
| Molecular Function | GO:0070628 | proteasome binding |
| Biological Process | GO:0051131 | chaperone-mediated protein complex assembly |
| Biological Process | GO:0080129 | proteasome core complex assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.