Search Results

Overview

Uniprot IDI3LTE8
Protein NameVesicle-fusing ATPase
Gene NameNSF
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
100 EIDFLQKKSIDSNPY
249 QMGCKHVKGILLYGP
634 KAPPQGRKLLIIGTT
703 KKVWIGIKKLLMLIE
723 DPEYRVRKFLALLRE

Function

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin

Protein Sequence

10 MQAARCPTDE 20 LSLSNCAVVN 30 EKDFQSGQHV 40 VVRTSPNHRY 50 TFTLRTHPSV 60 VPGSIAFSLP 70 QRKWAGLSIG 80 QEIEVSSYTF 90 DKAKQCIGTM 100 TMEIDFLQKK 110 SIDSNPYDTD 120 KMAAEFIQQF 130 NNQAFSVAQQ 140 LVFSFNEKLF 150 GLLVKDIEAM 160 DPSILKGEPG 170 TGKRQKIEVG 180 LVVGNSQVAF 190 EKAENSSLNL 200 IGKAKTKENR 210 QSIINPDWNF 220 EKMGIGGLDK 230 EFSDIFRRAF 240 ASRVFPPEIV 250 EQMGCKHVKG 260 ILLYGPPGCG 270 KTLLARQIGK 280 MLNAREPKVV 290 NGPEILNKYV 300 GESEANIRKL 310 FADAEEEQRR 320 LGANSGLHII 330 IFDEIDAICK 340 QRGSMAGSTG 350 VHDTVVNQLL 360 SKIDGVEQLN 370 NILVIGMTNR 380 PDLIDEALLR 390 PGRLEVKMEI 400 GLPDEKGRLQ 410 ILHIHTARMR 420 GHQLLSADVD 430 IKELAVETKN 440 FSGAELEGLV 450 RAAQSTAMNR 460 HIKASTKVEV 470 DMEKAESLQV 480 TRGDFLASLE 490 NDIKPAFGTN 500 QEDYASYIMN 510 GIIKWGDPVT 520 RVLEDGELLV 530 QQTKNSDRTP 540 LVSVLLEGPP 550 HSGKTALAAR 560 IAEESNFPFI 570 KICSPDKMIG 580 FSETAKTVDA 590 EKSECLEYVH 600 IYIEFLNNNN 610 ASLPDYVPIG 620 PRFSNLVLQA 630 LLVLLKKAPP 640 QGRKLLIIGT 650 TSRKDVLQEM 660 EMLNAFSTTI 670 HVPNIATGEQ 680 LLEALELLGN 690 FKDKERTTIA 700 QQVKGKKVWI 710 GIKKLLMLIE 720 MSLQMDPEYR 730 VRKFLALLRE 740 EGASERPSKE 750 MGCTVGLLSL 760 SCFAKLPCHS 770 AGKSSMVHIY 780 WNLLLNAWSC 790 DHFSFVKCTS 800 NSKCIEKNVE 810 KPLRSFLVFF 820 CDQQLFADPH 830 LFFCVCSGYF FQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0035255 ionotropic glutamate receptor binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0030165 PDZ domain binding
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0044877 protein-containing complex binding
Molecular Function GO:0017075 syntaxin-1 binding
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0045732 positive regulation of protein catabolic process
Biological Process GO:0001921 positive regulation of receptor recycling
Biological Process GO:0035494 SNARE complex disassembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.