Search Results
Overview
| Uniprot ID | I3LTI2 |
|---|---|
| Protein Name | Notchless protein homolog 1 |
| Gene Name | NLE1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 224 | RYVASSSKDGSVRVW |
Function
Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival
Protein Sequence
10
MAAAVADEAA
20
PRDVQRLLVQ
30
FQDEGGQLLG
40
SPFDVPVDIT
50
PDKLQLVCNA
60
LLAQEDPLPL
70
AFYVHDAEII
80
SSLGKTLESQ
90
AVETEKVLDI
100
IYQPQAVFRV
110
RAVTRCTSSL
120
EGHSEAVISV
130
AFSPTGKYLA
140
SGSGDTTVRF
150
WDLSTETPHF
160
TCQGHRHWVL
170
SISWSPDGKK
180
LASGCKNGQI
190
LLWDPSTGKQ
200
VGRALAGHSK
210
WITALSWEPL
220
HANPECRYVA
230
SSSKDGSVRV
240
WDTTAGRCER
250
ILTGHTQSVT
260
CLRWGGDGLL
270
YSASQDRTIK
280
VWRAHDGVLC
290
RTLQGHGHWV
300
NTMALSTDYA
310
LRTGAFEPAE
320
ASVNAQDLRG
330
SLQELKERAL
340
SRYNLVRGRG
350
LERLVSGSDD
360
FTLFLWSPAE
370
DKKPLARMTG
380
HQALINQVLF
390
SPDSRIIASA
400
SFDKSIKLWD
410
GRTGKYLASL
420
RGHVAAVYQI
430
AWSADSRLLV
440
SGSSDSTLKV
450
WDVKAQKLAA
460
DLPGHADEVY
470
AVDWSPDGQR
480
VASGGKDKCL
RIWRR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Biological Process | GO:0007219 | Notch signaling pathway |
| Biological Process | GO:0008593 | regulation of Notch signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.