Search Results
Overview
| Uniprot ID | I3LUJ5 |
|---|---|
| Protein Name | Calponin |
| Gene Name | CNN2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 134 | LAGKAKTKGLQSDVD |
| 19 | YGLSAEVKNRLLSKY |
| 234 | RRHIYDTKLGTDKCD |
| 25 | VKNRLLSKYDPQKEA |
| 30 | LSKYDPQKEAELRSW |
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Protein Sequence
10
MSSTQFNKGP
20
SYGLSAEVKN
30
RLLSKYDPQK
40
EAELRSWIEG
50
LTGLSIGPDF
60
QKGLKDGIIL
70
CTLMNKLQPG
80
SVPKINRSMQ
90
NWHQLENLSN
100
FIKAMVSYGM
110
NPVDLFEAND
120
LFESGNMTQV
130
QVSLLALAGK
140
AKTKGLQSDV
150
DIGVKYSEKQ
160
QRNFDDATMK
170
AGQCVIGLQM
180
GTNKCASQSG
190
MTAYGTRRHL
200
YDPKNHILPP
210
MDHSTISLQM
220
GTNKCASQVG
230
MTAPGTRRHI
240
YDTKLGTDKC
250
DNSSMSLQMG
260
YTQGANQSGQ
270
VFGLGRQIYD
280
PKYCPQGPAA
290
DGAPAAAGDC
300
PGPGESPEYP
310
PTTRRRRATE
320
VLLQALPPPL
330
PHVGFGVFPC
FCLVFLHS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0001725 | stress fiber |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0031032 | actomyosin structure organization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.