Search Results
Overview
| Uniprot ID | I3LVJ6 |
|---|---|
| Protein Name | Phosphatidylinositol-glycan biosynthesis class X protein |
| Gene Name | PIGX |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 55 | RDLLIRVKFGEGIED |
Function
Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM
Protein Sequence
10
GIEPAISWFL
20
VGFCLFYFKK
30
NLLVLLGIRA
40
TCSEIILKQE
50
VLKDGFHRDL
60
LIRVKFGEGI
70
EDLQTCRVLI
80
RQYIPTGLFV
90
DPYELASLRE
100
KNITEAVMVS
110
ENFNIEAPDY
120
LSKESEVLIY
130
ARQDPQCTDC
140
FQAFLPVHYR
150
YHRPHCNDEE
160
TFIVVNNPDL
170
LMYCDQEFPV
180
LKCWTQSEMT
190
APCALNSQDI
200
CQWNNMKYKS
210
VYKNVTLLVP
220
VGLTIHTSLV
230
CSVTLLVTVL
240
CSALILVAVF
TYGHFSL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Biological Process | GO:0006506 | GPI anchor biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.