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Overview

Uniprot IDK7GPS0
Protein NameDual specificity mitogen-activated protein kinase kinase 2
Gene NameMAP2K2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
108 KLIHLEIKPAIRNQI

Function

No function data available.

Protein Sequence

10 MLARRKPVLP 20 ALTINPAIAE 30 GPSPTSEGAS 40 EANLVDLQKK 50 LEELELDEQQ 60 KKRLEAFLTQ 70 KAKVGELKDD 80 DFERISELGA 90 GNGGVVTKVQ 100 HRPSGLIMAR 110 KLIHLEIKPA 120 IRNQIIRELQ 130 VLHECNSPYI 140 VGFYGAFYSD 150 GEISICMEHM 160 DGGSLDQVLK 170 EAKRIPEEIL 180 GKVSIAVLRG 190 LAYLREKHQI 200 MHRDVKPSNI 210 LVNSRGEIKL 220 CDFGVSGQLI 230 DSMANSFVGT 240 RSYMSPERLQ 250 GTHYSVQSDI 260 WSMGLSLVEL 270 SIGRYPIPPP 280 DAKELEAIFG 290 RPMVDGGDGE 300 PHSISPRPRP 310 PGRPISGHGM 320 DSRPAMAIFE 330 LLDYIVNEPP 340 PKLPNGVFTQ 350 DFQEFVNKCL 360 IKNPAERADL 370 KMLMNHTFIK 380 RSEVEEVDFA 390 GWLCKTLRLN 400 QPSTPTRTAV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005911 cell-cell junction
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:2000641 regulation of early endosome to late endosome transport
Biological Process GO:0090170 regulation of Golgi inheritance
Biological Process GO:0032872 regulation of stress-activated MAPK cascade
Cellular Component GO:0009898 cytoplasmic side of plasma membrane
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005769 early endosome
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0005794 Golgi apparatus
Cellular Component GO:0005770 late endosome
Cellular Component GO:0005874 microtubule
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0048471 perinuclear region of cytoplasm
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004708 MAP kinase kinase activity
Molecular Function GO:0005078 MAP-kinase scaffold activity
Molecular Function GO:0030165 PDZ domain binding
Molecular Function GO:0043539 protein serine/threonine kinase activator activity
Molecular Function GO:0004674 protein serine/threonine kinase activity
Molecular Function GO:0004713 protein tyrosine kinase activity
Molecular Function GO:0097110 scaffold protein binding
Biological Process GO:0070371 ERK1 and ERK2 cascade
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0045893 positive regulation of DNA-templated transcription

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.