Search Results
Overview
| Uniprot ID | K7GRR0 |
|---|---|
| Protein Name | - |
| Gene Name | LDLR |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 285 | CEGPNKFKCQSGECI |
Function
No function data available.
Protein Sequence
10
MKSTGWVLRW
20
AVALLIAAVA
30
AAVEEKCGRN
40
EFQCRDGKCI
50
SYKWICDGNT
60
ECKDGSDESL
70
ETCMSVTCKI
80
GDFSCGGRVN
90
RCIPESWRCD
100
GQQDCENGSD
110
EEGCSPKTCS
120
QDEFRCQDGK
130
CIAPKFVCDS
140
DRDCLDGSDE
150
ASCPTPTCGP
160
ASFQCNSSTC
170
IPELWACDGD
180
PDCEDGSDEW
190
PQHCRSHSSS
200
LPERSNNPCS
210
ALEFHCHSGE
220
CIHSSWRCDG
230
DTDCKDKSDE
240
ENCDVATCRP
250
DEFQCSDGTC
260
IHGSRQCDRE
270
YDCKDLSDEQ
280
GCVNVTLCEG
290
PNKFKCQSGE
300
CISLDKVCNS
310
VRDCRDWSDE
320
PLKECGTNEC
330
LDNKGGCSHI
340
CNDLKIGYEC
350
LCPEGFQLVD
360
KHRCEDIDEC
370
QDPDACSQIC
380
VNLEGSYKCQ
390
CEEGFQLEPL
400
TKACKAIGTI
410
AYLFFTNRHE
420
VRKMTLDRSE
430
YTSLIPNLKN
440
VVALDTEVAS
450
NRIYWSDLSQ
460
RKIYSTQINR
470
APSFSSYDTI
480
IGEDLQAPDG
490
LAVDWIHSNI
500
YWTDSILGTV
510
SVADTKGVKR
520
KTLFQEKGSK
530
PRAIVAPAWF
540
RGMGGAFLGT
550
SLLGLGGLPP
560
GGAGCQGPQA
570
YCVTSPCPPP
580
WVLDLSGGRL
590
YWVDSKLHSI
600
SSIDVNGGNR
610
KTVLEDKTKL
620
AHPFSLAIFE
630
DKVFWTDVIN
640
EAIFSANRLT
650
GSDIHLMAEN
660
LLSPEDIVLF
670
HNLTQPRGVN
680
WCERTALQNG
690
GCQYLCLPAP
700
QINPRSPKFT
710
CACPDGMLLA
720
KDMRSCLTET
730
EPAGTTQGPS
740
MVNSTAVGPK
750
HTASSELTTA
760
ESVTMSQHAL
770
GDVAGRGVTE
780
KPQSVGALYI
790
VLPIALLILL
800
FFGTFLLWKN
810
WRLKSINSIN
820
FDNPVYQKTT
830
EDEVHICRSQ
840
DGYTYPSRQM
VSLEDDVA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0045177 | apical part of cell |
| Cellular Component | GO:0016323 | basolateral plasma membrane |
| Cellular Component | GO:0005905 | clathrin-coated pit |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0009897 | external side of plasma membrane |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005770 | late endosome |
| Cellular Component | GO:0005764 | lysosome |
| Cellular Component | GO:1990666 | PCSK9-LDLR complex |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0043235 | receptor complex |
| Cellular Component | GO:0036477 | somatodendritic compartment |
| Cellular Component | GO:0097443 | sorting endosome |
| Molecular Function | GO:0001540 | amyloid-beta binding |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0071813 | lipoprotein particle binding |
| Molecular Function | GO:0030169 | low-density lipoprotein particle binding |
| Molecular Function | GO:0005041 | low-density lipoprotein particle receptor activity |
| Molecular Function | GO:0002020 | protease binding |
| Molecular Function | GO:0030229 | very-low-density lipoprotein particle receptor activity |
| Biological Process | GO:0150094 | amyloid-beta clearance by cellular catabolic process |
| Biological Process | GO:0048844 | artery morphogenesis |
| Biological Process | GO:0071398 | cellular response to fatty acid |
| Biological Process | GO:0071404 | cellular response to low-density lipoprotein particle stimulus |
| Biological Process | GO:0042632 | cholesterol homeostasis |
| Biological Process | GO:0070508 | cholesterol import |
| Biological Process | GO:0034384 | high-density lipoprotein particle clearance |
| Biological Process | GO:0030299 | intestinal cholesterol absorption |
| Biological Process | GO:0007616 | long-term memory |
| Biological Process | GO:0034383 | low-density lipoprotein particle clearance |
| Biological Process | GO:1905907 | negative regulation of amyloid fibril formation |
| Biological Process | GO:0061889 | negative regulation of astrocyte activation |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:0010989 | negative regulation of low-density lipoprotein particle clearance |
| Biological Process | GO:1903979 | negative regulation of microglial cell activation |
| Biological Process | GO:0001920 | negative regulation of receptor recycling |
| Biological Process | GO:0006909 | phagocytosis |
| Biological Process | GO:0015914 | phospholipid transport |
| Biological Process | GO:0010628 | positive regulation of gene expression |
| Biological Process | GO:0050729 | positive regulation of inflammatory response |
| Biological Process | GO:1905167 | positive regulation of lysosomal protein catabolic process |
| Biological Process | GO:0010867 | positive regulation of triglyceride biosynthetic process |
| Biological Process | GO:0090118 | receptor-mediated endocytosis involved in cholesterol transport |
| Biological Process | GO:0090181 | regulation of cholesterol metabolic process |
| Biological Process | GO:0010899 | regulation of phosphatidylcholine catabolic process |
| Biological Process | GO:0061771 | response to caloric restriction |
| Biological Process | GO:0001523 | retinoid metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.