Search Results
Overview
| Uniprot ID | K7GSI9 |
|---|---|
| Protein Name | Four and a half LIM domains protein 1 |
| Gene Name | FHL1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 107 | NTCVECRKPIGADSK |
| 114 | KPIGADSKEVHYKNR |
| 148 | TFMAKDNKILCNKCT |
| 153 | DNKILCNKCTTREDS |
| 168 | PKCKGCFKPIVAGDQ |
| 180 | GDQNVEYKGTVWHKD |
| 186 | YKGTVWHKDCFTCSN |
| 206 | GTGSFFPKGEDFYCV |
| 219 | CVTCHETKFAKHCVK |
| 222 | CHETKFAKHCVKCNK |
| 226 | KFAKHCVKCNKAITS |
| 287 | AKKCAGCKNPITGFG |
| 295 | NPITGFGKGSSVVAY |
| 315 | HDYCFHCKKCSVNLA |
| 316 | DYCFHCKKCSVNLAN |
| 324 | CSVNLANKRFVFHQE |
| 340 | VYCPDCAKKL***** |
| 84 | QGKKYVQKDGHHCCL |
| 92 | DGHHCCLKCFDKFCA |
Function
May have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcription in mammalian systems
Protein Sequence
10
MYVHNGAAAL
20
SAGPRGQWLQ
30
VRLGTRWRSH
40
GLPQTCRPCL
50
PLMLFPGQKR
60
SCSGPSSYKV
70
GTMAEKFDCH
80
YCRDPLQGKK
90
YVQKDGHHCC
100
LKCFDKFCAN
110
TCVECRKPIG
120
ADSKEVHYKN
130
RYWHDTCFRC
140
SKCLHPLANE
150
TFMAKDNKIL
160
CNKCTTREDS
170
PKCKGCFKPI
180
VAGDQNVEYK
190
GTVWHKDCFT
200
CSNCKQVIGT
210
GSFFPKGEDF
220
YCVTCHETKF
230
AKHCVKCNKA
240
ITSGGITYQD
250
QPWHAECFVC
260
VTCSKKLAGQ
270
RFTAVEDQYY
280
CVDCYKNFVA
290
KKCAGCKNPI
300
TGFGKGSSVV
310
AYEGQSWHDY
320
CFHCKKCSVN
330
LANKRFVFHQ
340
EQVYCPDCAK
KL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0007517 | muscle organ development |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.