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Overview

Uniprot IDK7GT04
Protein NameStress-activated protein kinase JNK
Gene NameMAPK10
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
160 KPSNIVVKSDCTLKI
227 PCPEFMKKLQPTVRN

Function

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity

Protein Sequence

10 MSKSKVDNQF 20 YSVEVGDSTF 30 TVLKRYQNLK 40 PIGSGAQGIV 50 CAAYDAVLDR 60 NVAIKKLSRP 70 FQNQTHAKRA 80 YRELVLMKCV 90 NHKNIISLLN 100 VFTPQKTLEE 110 FQDVYLVMEL 120 MDANLCQVIQ 130 MELDHERMSY 140 LLYQMLCGIK 150 HLHSAGIIHR 160 DLKPSNIVVK 170 SDCTLKILDF 180 GLARTAGTSF 190 MMTPYVVTRY 200 YRAPEVILGM 210 GYKENDIDQW 220 NKVIEQLGTP 230 CPEFMKKLQP 240 TVRNYVENRP 250 KYAGLTFPKL 260 FPDSLFPADS 270 EHNKLKASQA 280 RDLLSKMLVI 290 DPAKRISVDD 300 ALQHPYINVW 310 YDPAEVEAPP 320 PQIYDKQLDE 330 REHTIEEWKE 340 LIYKEVMLSE 350 EKTKNGVVKG 360 QPSPSGAAVN 370 SSESLPPSSS 380 VNDISSMSTD 390 QTLASDTDSS 400 LEASAGPLGC CR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0004707 MAP kinase activity
Molecular Function GO:0106310 protein serine kinase activity
Biological Process GO:0048511 rhythmic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.