Search Results

Overview

Uniprot IDK9IVE3
Protein NameCasein kinase II subunit alpha
Gene NameCSNK2A2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
230 LASMIFRKEPFFHGQ
84 KKIKREVKILENLRG

Function

Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine

Protein Sequence

10 MPGPAAGSRA 20 RVYAEVNSLR 30 SREYWDYESH 40 VPSWGNQDDY 50 QLVRKLGRGK 60 YSEVFEAINI 70 TNNERVVVKI 80 LKPVKKKKIK 90 REVKILENLR 100 GGTNIIKLID 110 TVKDPVSKTP 120 ALVFEYINNT 130 DFKQLYQILT 140 DFDIRFYMYE 150 LLKALDYCHS 160 KGIMHRDVKP 170 HNVMIDHQQK 180 KLRLIDWGLA 190 EFYHPAQEYN 200 VRVASRYFKG 210 PELLVDYQMY 220 DYSLDMWSLG 230 CMLASMIFRK 240 EPFFHGQDNY 250 DQLVRIAKVL 260 GTDELYGYLK 270 KYHIDLDPHF 280 NDILGQHSRK 290 RWENFIHSEN 300 RHLVSPEALD 310 LLDKLLRYDH 320 QQRLTAKEAM 330 EHPYFYPVVK 340 EQSQPCADNA 350 VLSSGLTAAR

Gene Ontology

Classification GO ID Description
Molecular Function GO:0004674 protein serine/threonine kinase activity
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005634 nucleus
Cellular Component GO:0031519 PcG protein complex
Cellular Component GO:0005956 protein kinase CK2 complex
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0106310 protein serine kinase activity
Biological Process GO:0006974 DNA damage response
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Process GO:1905818 regulation of chromosome separation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.